1223-45-6

Basic information

• Product Name: N-(4-methoxyphenyl)-N'-(4-methylphenyl)thiourea
• Synonyms: N-(4-methoxyphenyl)-N'-(4-methylphenyl)thiourea
• CAS NO: 1223-45-6
• Molecular Weight: 272.371
• Mol File: 1223-45-6.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: N-(4-methoxyphenyl)-N'-(4-methylphenyl)thiourea(CAS DataBase Reference)
• NIST Chemistry Reference: N-(4-methoxyphenyl)-N'-(4-methylphenyl)thiourea(1223-45-6)
• EPA Substance Registry System: N-(4-methoxyphenyl)-N'-(4-methylphenyl)thiourea(1223-45-6)

Safety Data

• Hazardous Substances Data: 1223-45-6(Hazardous Substances Data)

Upstream product

• 106-49-0 p-toluidine 
• 2284-20-0 4-Methoxyphenyl isothiocyanate 
• 22517-50-6 o-phenyl p-tolylcarbamothioate 
• 104-94-9 4-methoxy-aniline 
• 75-15-0 carbon disulfide 
• 622-59-3 1-isothiocyanato-4-methylbenzene 

Downstream Products

• 7669-37-6 [3-(4-methoxy-phenyl)-4-oxo-2-p-tolylimino-thiazolidin-5-yl]-acetic acid 
• 7669-38-7 [2-(4-methoxy-phenylimino)-4-oxo-3-p-tolyl-thiazolidin-5-yl]-acetic acid 
• 28250-85-3 2-(4-methoxy-phenylimino)-5-methyl-3-p-tolyl-thiazolidin-4-one 

Relevant articles and documents

Synthesis of thiazol, thiazinan, thiadiazin, thiazolidin, triazine, thioxo-pyrimidin and thioxo-imidazolidine by inter-intra molecular cyclization

Syntheses of five and six membered heterocyclic derivatives by the reaction of disubstituted thiocarbamides with interintramolecular cyclizations in catalyst free condition have been reported. The simple product isolation without column, good yields under mild condition, and applicable green matrix are the advantages of present protocol.

A simple and straightforward synthesis of phenyl isothiocyanates, symmetrical and unsymmetrical thioureas under ball milling

Promoted by KOH under ball milling, anilines were efficiently transformed into isothiocyanates (in presence of 5.0 equiv. CS2) or symmetrical thioureas (in presence of 1.0 equiv. CS2), without using any other harsh or toxic decomposition reagent. Some in situ generated isothiocyanates can directly "click" with other amines to afford unsymmetrical thioureas.

Potential Fungicides: Studies of 2-Arylimino-3-aryl-4-thiazolidinones, Their 1,1-Dioxides and 5-Phenylazo Derivatives

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