1228027-28-8

Basic information

• Product Name: tert-butyl methyl((S)-1-oxo-1-((3aR,4S,6aS)-2-(4-(trifluoromethyl)phenylsulfonyl)octahydrocyclopenta[c]pyrrol-4-ylamino)hexan-2-yl)carbamate
• CAS NO: 1228027-28-8
• Molecular Weight: 561.666
• Mol File: 1228027-28-8.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: tert-butyl methyl((S)-1-oxo-1-((3aR,4S,6aS)-2-(4-(trifluoromethyl)phenylsulfonyl)octahydrocyclopenta[c]pyrrol-4-ylamino)hexan-2-yl)carbamate(CAS DataBase Reference)
• NIST Chemistry Reference: tert-butyl methyl((S)-1-oxo-1-((3aR,4S,6aS)-2-(4-(trifluoromethyl)phenylsulfonyl)octahydrocyclopenta[c]pyrrol-4-ylamino)hexan-2-yl)carbamate(1228027-28-8)
• EPA Substance Registry System: tert-butyl methyl((S)-1-oxo-1-((3aR,4S,6aS)-2-(4-(trifluoromethyl)phenylsulfonyl)octahydrocyclopenta[c]pyrrol-4-ylamino)hexan-2-yl)carbamate(1228027-28-8)

Safety Data

• Hazardous Substances Data: 1228027-28-8(Hazardous Substances Data)

Upstream product

• 1349980-80-8 (3aR,4R,6aS)-2-benzyloctahydrocyclopenta[c]pyrrol-4-ol 
• 1228030-25-8 (3aR,4S,6aS)-2-(4-(trifluoromethyl)phenylsulfonyl)octahydrocyclopenta[c]pyrrol-4-amine 
• 117903-25-0 N-BOC-N-methylnorleucine 
• 1228030-08-7 tert-butyl (3aR,4S,6aS)-octahydrocyclopenta[c]pyrrol-4-ylcarbamate 
• 1228030-06-5 tert-butyl (3aR,4S,6aS)-2-benzyloctahydrocyclopenta[c]pyrrol-4-ylcarbamate 
• 874949-33-4 (3aR,4S,6aS)-2-(phenylmethyl)octahydrocyclopenta[c]pyrrol-4-amine 
• 939033-18-8 C₁₅H₂₁NO₃S 

Downstream Products

• 1228028-03-2 N₂-methyl-N₁-((3aR,4S,6aS)-2-{[4-(trifluoromethyl)phenyl]sulfonyl}octahydrocyclopenta[c]pyrrol-4-yl)-L-norleucinamide 

Relevant articles and documents

Synthesis and SAR of 4-aminocyclopentapyrrolidines as orally active N-type calcium channel inhibitors for inflammatory and neuropathic pain

A novel series of N-type calcium channel inhibitors have been discovered. Optimization of potency and HT-ADME properties provides 4- aminocyclopentapyrrolidines with analgesic efficacy after oral dosing.