1228150-85-3

Basic information

• Product Name: C₂₃H₁₇FN₂O₂
• Synonyms: C₂₃H₁₇FN₂O₂
• CAS NO: 1228150-85-3
• Molecular Weight: 372.399
• Mol File: 1228150-85-3.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: C₂₃H₁₇FN₂O₂(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₃H₁₇FN₂O₂(1228150-85-3)
• EPA Substance Registry System: C₂₃H₁₇FN₂O₂(1228150-85-3)

Safety Data

• Hazardous Substances Data: 1228150-85-3(Hazardous Substances Data)

Upstream product

• 1953-54-4 indol-5-ol 
• 459-57-4 4-fluorobenzaldehyde 

Relevant articles and documents

FeCl3·6H2O as a Mild Catalyst for Nucleophilic Substitution of Symmetrical Bis(indoyl)methanes

In this paper, unsymmetrical bis(indolyl)methane (BIM) and 3-alkylindole derivatives are smoothly synthesized from symmetrical BIMs with a variety of nucleophiles including heteroaromatic/aromatic compounds, allylsilane and alkynylsilane. FeCl3·6H2O is found to be a mild and highly effective catalyst for this nucleophilic substitution reaction in which N-methyl-2-phenylindole behaves as a good leaving group in the Csp3-Csp2 bond cleavage reaction. The operational ease, nonexpensive and environmentally friendly catalyst, mild reaction conditions, broad functional group tolerance, and scalability of this reaction strategy are advantages of the present procedure.