122841-12-7 Usage
Description
Cefoselis sulfate is a fourth-generation cephalosporin antibiotic, launched in Japan under the brand name Wincef. It is effective against a variety of infections, including methicillin-resistant Staphylococcus aureus (MRSA) and Pseudomonas aeruginosa. Cefoselis sulfate demonstrates better minimum inhibitory concentration (MIC50) values compared to Ceftazidime against Streptococcus pneumoniae and Staphylococcus aureus (both methicillin-sensitive MSSA and resistant MRSA). Additionally, it exhibits significant antibacterial activity against Citrobacter and Enterobacter species. Cefoselis sulfate is well-tolerated in clinical studies and is primarily eliminated through glomerular filtration in humans.
Uses
Used in Pharmaceutical Industry:
Cefoselis sulfate is used as an antibiotic for treating a range of bacterial infections, particularly those caused by methicillin-resistant Staphylococcus aureus (MRSA) and Pseudomonas aeruginosa. Its effectiveness against various bacterial strains, including Streptococcus pneumoniae, Citrobacter, and Enterobacter, makes it a valuable addition to the arsenal of antibiotics for combating drug-resistant infections.
Originator
Fujisawa (Japan)
Check Digit Verification of cas no
The CAS Registry Mumber 122841-12-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,2,8,4 and 1 respectively; the second part has 2 digits, 1 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 122841-12:
(8*1)+(7*2)+(6*2)+(5*8)+(4*4)+(3*1)+(2*1)+(1*2)=97
97 % 10 = 7
So 122841-12-7 is a valid CAS Registry Number.
InChI:InChI=1/C19H22N8O6S2.H2O4S/c1-33-24-12(10-8-35-19(21)22-10)15(29)23-13-16(30)27-14(18(31)32)9(7-34-17(13)27)6-25-3-2-11(20)26(25)4-5-28;1-5(2,3)4/h2-3,8,13,17,20,28H,4-7H2,1H3,(H4,21,22,23,29,31,32);(H2,1,2,3,4)/b24-12+;/t13-,17-;/m1./s1