1231747-10-6

Basic information

• Product Name: (2S)isopropyl 2-((((2R,3R,4R,5R) 5-(2-amino-6-methoxy-9H-purin-9-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(phenoxy)phosphorylamino)propanoate
• CAS NO: 1231747-10-6
• Molecular Weight: 582.526
• Mol File: 1231747-10-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (2S)isopropyl 2-((((2R,3R,4R,5R) 5-(2-amino-6-methoxy-9H-purin-9-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(phenoxy)phosphorylamino)propanoate(CAS DataBase Reference)
• NIST Chemistry Reference: (2S)isopropyl 2-((((2R,3R,4R,5R) 5-(2-amino-6-methoxy-9H-purin-9-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(phenoxy)phosphorylamino)propanoate(1231747-10-6)
• EPA Substance Registry System: (2S)isopropyl 2-((((2R,3R,4R,5R) 5-(2-amino-6-methoxy-9H-purin-9-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(phenoxy)phosphorylamino)propanoate(1231747-10-6)

Safety Data

• Hazardous Substances Data: 1231747-10-6(Hazardous Substances Data)

Upstream product

• 261909-49-3 phenyl(isopropoxy-L-alaninyl) phosphorochloridate 
• 1199809-27-2 (2R,3R,4R,5R)-5-(2-amino-6-methoxy-9H-purin-9-yl)-4-fluoro-2-(hydroxymethyl)-4-methyltetrahydrofuran-3-ol 

Downstream Products

• 1261254-19-6 C₂₄H₃₁BrFN₆O₈P 
• 1261254-20-9 C₂₄H₃₁⁽³⁾HFN₆O₈P 

Relevant articles and documents

Discovery of PSI-353661, a novel purine nucleotide prodrug for the treatment of HCV infection

Hepatitis C virus afflicts approximately 180 million people worldwide, and the development of direct acting antivirals may offer substantial benefit compared to the current standard of care. Accordingly, prodrugs of 2′-deoxy-2′-fluoro-2′-C-methylguanosine