124705-76-6

Basic information

• Product Name: C₃₆H₄₀N₂O₁₃
• Synonyms: C₃₆H₄₀N₂O₁₃
• CAS NO: 124705-76-6
• Molecular Weight: 708.719
• Mol File: 124705-76-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₃₆H₄₀N₂O₁₃(CAS DataBase Reference)
• NIST Chemistry Reference: C₃₆H₄₀N₂O₁₃(124705-76-6)
• EPA Substance Registry System: C₃₆H₄₀N₂O₁₃(124705-76-6)

Safety Data

• Hazardous Substances Data: 124705-76-6(Hazardous Substances Data)

Upstream product

• 33419-42-0 etoposide 
• 124816-28-0 (5R,6R,7R,8S)-8-((2R,4aR,6R,7R,8R,8aS)-7,8-Dihydroxy-2-methyl-hexahydro-pyrano[3,2-d][1,3]dioxin-6-yloxy)-5-(4-hydroxy-3,5-dimethoxy-phenyl)-7-hydroxymethyl-5,6,7,8-tetrahydro-naphtho[2,3-d][1,3]dioxole-6-carboxylic acid hydrazide 
• 100-52-7 benzaldehyde 

Downstream Products

• 124705-61-9 C₃₆H₃₈N₂O₁₂ 
• 124705-62-0 (5R,5aR,8aR,9S)-7-Benzylamino-9-((2R,4aR,6R,7R,8R,8aS)-7,8-dihydroxy-2-methyl-hexahydro-pyrano[3,2-d][1,3]dioxin-6-yloxy)-5-(4-hydroxy-3,5-dimethoxy-phenyl)-5,5a,7,8,8a,9-hexahydro-1,3-dioxa-7-aza-dicyclopenta[b,g]naphthalen-6-one 
• 124705-63-1 (5R,5aR,8aR,9S)-9-((2R,4aR,6R,7R,8R,8aS)-7,8-Dihydroxy-2-methyl-hexahydro-pyrano[3,2-d][1,3]dioxin-6-yloxy)-5-(4-hydroxy-3,5-dimethoxy-phenyl)-5,5a,7,8,8a,9-hexahydro-1,3-dioxa-7-aza-dicyclopenta[b,g]naphthalen-6-one 
• 124705-61-9 6H-Pyrrolo[3',4':6,7]naphtho[2,3-d]-1,3-dioxole-6-one, 5,5a,7,8,8a,9-hexahydro-9-[(4,6-O-ethylidene-β-D-glucopyranosyl)oxy]-5-[(4-hydroxy-3,5-dimethoxy)phenyl]-7-[(phenylmethylene)amino][5R-[5α,5aβ,8aα,9β(R*)]- 

Relevant articles and documents

SYNTHESIS OF ETOPOSIDE LACTAM VIA A MITSUNOBU REACTION SEQUENCE

A novel chemical sequence for the conversion of a lactone antitumor agent 1 (etoposide) to the corresponding lactam 2 is described.The key steps involve a Mitsunobu cyclization (Ph3P, DEAD) of the γ-hydroxymethyl acyl benzaldehyde hydrazone 6 to a lactam derivative 7 followed by reductive cleavage (Ra-Ni) to lactam 2.