124851-36-1

Basic information

• Product Name: (E)-2-styryl-3,4-dihydro-2H-pyran
• Synonyms: (E)-2-styryl-3,4-dihydro-2H-pyran
• CAS NO: 124851-36-1
• Molecular Weight: 186.254
• Mol File: 124851-36-1.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: (E)-2-styryl-3,4-dihydro-2H-pyran(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-2-styryl-3,4-dihydro-2H-pyran(124851-36-1)
• EPA Substance Registry System: (E)-2-styryl-3,4-dihydro-2H-pyran(124851-36-1)

Safety Data

• Hazardous Substances Data: 124851-36-1(Hazardous Substances Data)

Upstream product

• 929906-56-9 (E)-2-styryl-3,6-dihydro-2H-pyran 
• 14371-10-9 (E)-3-phenylpropenal 
• 79299-29-9 (E)-1-phenyl-1,5-hexadien-3-ol 
• 135218-48-3 (E)-(3-(allyloxy)hexa-1,5-dien-1-yl)benzene 
• 100-73-2 acrolein dimer 
• 1449-46-3 benzyltriphenylphosphonium bromide 
• 100-39-0 benzyl bromide 
• 3749-36-8 2-hydroxymethyl-3,4-dihydro-2H-pyran 

Downstream Products

• 17303-67-2 (2'E)-6-(2'phenylvinyl)-5,6-dihydro-2H-pyran-2-one 
• 124851-40-7 6-tert-Butylperoxy-2-((E)-styryl)-3,6-dihydro-2H-pyran 

Relevant articles and documents

Design, synthesis, in vitro cytotoxicity evaluation and structure-activity relationship of Goniothalamin analogs

A series of six/five member (E/Z)-Goniothalamin analogs were synthesized from commercially available (3,4-dihydro-2H-pyran-2-yl)methanol/5- (hydroxymethyl)dihydrofuran-2(3H)-one in three steps with good to moderate overall yields and their cytotoxicity against lymphoblastic leukemic T cell line (Jurkat E6.1) have been evaluated. Among the synthesized analogs, (Z)-Goniothalamin appeared to be the most active in cytotoxicity (IC 50 = 12 μM). Structure-activity relationship study indicates that introducing substituent in phenyl ring or replacing phenyl ring by pyridine/naphthalene, or decreasing the ring size of lactones (from six to five member) do not increase the cytotoxicity.

In situ conversion of a Ru metathesis catalyst to an isomerization catalyst

Addition of alcohols and substoichiometric amounts of a base to a metathesis reaction induces conversion of the metathesis-active carbene catalyst to an isomerization-active hydride species.