124961-78-0Relevant articles and documents
Studies on the constituents of Actinostemma lobatum MAXIM. V. Structures of Lobatosides B,E,F and G, the dicrotalic acid esters of bayogenin bisdesmosides isolated from the herb
Fujioka, Toshihiro,Iwamoto, Masayo,Iwase, Yukiko,Hachiyama, Shizuko,Okabe, Hikaru,et al.
, p. 2355 - 2360 (2007/10/02)
The structures of lobatosides B, E, F and G, the dicrotalic acid esters of bayogenin bisdesmosides isolated from the herb of Actinostemma lobatum MAXIM. (Cucurbitaceae), were determined on the basis of chemical and spectral evidence.Lobatoside B is the dicrotalic acid (3-hydroxy-3-methylglutaric acid ) ester of 3-O-2)-β-D-glucopyranosyl>bayogenin 28-2)-α-L-arabinopyranosyl> ester.Dicrotalic acid is linked at one end to the C6-hydroxyl group of the terminal β-D-glucopyranosyl group in the C3-linked sugar moiety, and at the other end to the C4-hydroxyl group of the α-L-rhamnopyranosyl group in the ester-linked sugar moiety to form a macrocyclic structure (cyclic bisdesmoside).Lobatosides E, F and G are cyclic bisdesmosides of bayogenin similar to lobatoside B, but different in the numbers and species of the component sugars and positions of the ester linkages of the dicrotalic acid.Keywords - Actinostemma lobatum; Cucurbitaceae; lobatoside; bayogenin glycoside; cyclic bisdesmoside; dicrotalic acid; NOE difference spectrum; decoupling difference spectrum.