1253769-13-9
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Basic information
- Product Name: (Z)-1-acetyl-3-(methoxy-phenyl-methylene)-2-oxo-2,3-dihydro-1H-indole-6-carboxylic acid methyl ester
- Synonyms: (Z)-1-acetyl-3-(methoxy-phenyl-methylene)-2-oxo-2,3-dihydro-1H-indole-6-carboxylic acid methyl ester
- CAS NO:1253769-13-9
- Molecular Formula:
- Molecular Weight: 351.359
- EINECS: N/A
- Product Categories: N/A
- Mol File: 1253769-13-9.mol
- Article Data: 0
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Chemical Properties
- Melting Point: N/A
- Boiling Point: N/A
- Flash Point: N/A
- Appearance: N/A
- Density: N/A
- Refractive Index: N/A
- Storage Temp.: N/A
- Solubility: N/A
- CAS DataBase Reference: (Z)-1-acetyl-3-(methoxy-phenyl-methylene)-2-oxo-2,3-dihydro-1H-indole-6-carboxylic acid methyl ester(CAS DataBase Reference)
- NIST Chemistry Reference: (Z)-1-acetyl-3-(methoxy-phenyl-methylene)-2-oxo-2,3-dihydro-1H-indole-6-carboxylic acid methyl ester(1253769-13-9)
- EPA Substance Registry System: (Z)-1-acetyl-3-(methoxy-phenyl-methylene)-2-oxo-2,3-dihydro-1H-indole-6-carboxylic acid methyl ester(1253769-13-9)
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Safety Data
- Hazard Codes: N/A
- Statements: N/A
- Safety Statements: N/A
- WGK Germany:
- RTECS:
- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 1253769-13-9(Hazardous Substances Data)
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1253769-13-9 Usage
Description
(Z)-1-acetyl-3-(methoxy-phenyl-methylene)-2-oxo-2,3-dihydro-1H-indole-6-carboxylic acid methyl ester, also known as (Z)-Methyl 1-Acetyl-3-(methoxy(phenyl)methylene)-2-oxoindoline-6-carboxylate, is a chemical compound with a complex structure. It is an impurity found in Nintedanib (N478290), which is an angiokinase inhibitor used in the treatment of idiopathic pulmonary fibrosis. (Z)-1-acetyl-3-(methoxy-phenyl-methylene)-2-oxo-2,3-dihydro-1H-indole-6-carboxylic acid methyl ester has the potential to inhibit blood vessel formation, making it a valuable compound for further research and development in the medical field.Uses
Used in Pharmaceutical Industry:(Z)-1-acetyl-3-(methoxy-phenyl-methylene)-2-oxo-2,3-dihydro-1H-indole-6-carboxylic acid methyl ester is used as an impurity in the production of Nintedanib (N478290) for the treatment of idiopathic pulmonary fibrosis. Its presence in the drug may contribute to the overall therapeutic effects of Nintedanib.
Used in Cancer Therapy:
(Z)-1-acetyl-3-(methoxy-phenyl-methylene)-2-oxo-2,3-dihydro-1H-indole-6-carboxylic acid methyl ester is used as a potential inhibitor of blood vessel formation, which is a crucial process for cancer growth and metastasis. By inhibiting this process, it may assist in cancer therapy and be a valuable compound for the development of new anticancer drugs.
Check Digit Verification of cas no
The CAS Registry Mumber 1253769-13-9 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,5,3,7,6 and 9 respectively; the second part has 2 digits, 1 and 3 respectively.Calculate Digit Verification of CAS Registry Number 1253769-13:
(9*1)+(8*2)+(7*5)+(6*3)+(5*7)+(4*6)+(3*9)+(2*1)+(1*3)=169
169 % 10 = 9
So 1253769-13-9 is a valid CAS Registry Number.
1253769-13-9Upstream product
1253769-13-9Downstream Products
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(Z)-1-acetyl-3-(methoxy-phenyl-methylene)-2-oxo-2,3-dihydro-1H-indole-6-carboxylic acid methyl ester
