1256338-86-9Relevant articles and documents
A new strategy for the chemoselective sulfonamide N-alkylation of sulfonyl ureas under neutral and mild conditions
Adib, Mehdi,Sheikhi, Ehsan,Moghaddam, Gita Sheikhi,Bijanzadeh, Hamid Reza
scheme or table, p. 5646 - 5648 (2010/11/18)
An efficient and chemoselective sulfonamide N-alkylation of sulfonyl ureas is described. The sulfonyl urea derivatives, prepared in situ by the addition of an amine to an arylsulfonyl isocyanate, are selectively alkylated in excellent yields under neutral and mild conditions by treatment with trialkylphosphite- dimethyl acetylenedicarboxylate at ambient temperature.
