126216-75-9

Basic information

• Product Name: (2,6-Bis-benzotriazol-1-yl-piperidin-1-yl)-carbamic acid benzyl ester
• Synonyms: (2,6-Bis-benzotriazol-1-yl-piperidin-1-yl)-carbamic acid benzyl ester
• CAS NO: 126216-75-9
• Molecular Weight: 468.518
• Mol File: 126216-75-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (2,6-Bis-benzotriazol-1-yl-piperidin-1-yl)-carbamic acid benzyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (2,6-Bis-benzotriazol-1-yl-piperidin-1-yl)-carbamic acid benzyl ester(126216-75-9)
• EPA Substance Registry System: (2,6-Bis-benzotriazol-1-yl-piperidin-1-yl)-carbamic acid benzyl ester(126216-75-9)

Safety Data

• Hazardous Substances Data: 126216-75-9(Hazardous Substances Data)

Upstream product

• 95-14-7 1,2,3-Benzotriazole 
• 5331-43-1 N-benzyloxycarbonyl-hydrazine 
• 111-30-8 Glutaraldehyde 

Downstream Products

• 126216-46-4 Piperidin-1-yl-carbamic acid benzyl ester 

Relevant articles and documents

A Novel and Versatile Synthesis of 1-Alkyl-, 1-Aryl-, 1-(Alkylamino)-, or 1-Amido-Substituted and of 1,2,6-Trisubstituted Piperidines from Glutaraldehyde and Primary Amines or Monosubstituted Hydrazines

Various primary amines and 1-mono- and 1,1-disubstituted hydrazines were converted into the corresponding N-substituted piperidines in good to excellent yields via the products of double condensations with benzotriazole and glutaraldehyde.Reduction of the 2,6-bis(benzotriazolyl) N-substituted piperidines 4 and 7 with sodium borohydride in tetrahydrofuran afforded N-substituted piperidines.The benzotriazole moieties were also replaced by alkyl groups by reaction with Grignard reagents to produce 1,2,6-trisubstituted piperidines.