1262985-23-8 Usage
Description
1-Propanesulfonamide, N-[3-[[5-(4-chlorophenyl)-1-(2,6-dichlorobenzoyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]carbonyl]-2,4-difluorophenyl]is a chemical compound with a complex structure, featuring a propanesulfonamide backbone and a substituted phenyl group. It is characterized by the presence of various functional groups, including a sulfonyl, amide, and fluoro groups, as well as a chlorophenyl and dichlorobenzoyl moiety. 1-Propanesulfonamide, N-[3-[[5-(4-chlorophenyl)-1-(2,6-dichlorobenzoyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]carbonyl]-2,4-difluorophenyl]is known for its potential applications in the pharmaceutical industry.
Uses
Used in Pharmaceutical Industry:
1-Propanesulfonamide, N-[3-[[5-(4-chlorophenyl)-1-(2,6-dichlorobenzoyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]carbonyl]-2,4-difluorophenyl]is used as a reagent for the preparation of solid state forms of pharmaceutical compounds. Specifically, it is utilized in the synthesis of vemurafenib choline salt, a medication used to treat melanoma, a type of skin cancer. The solid state form of vemurafenib choline salt is desirable for its improved stability, solubility, and bioavailability, which can enhance the drug's efficacy and safety profile.
Check Digit Verification of cas no
The CAS Registry Mumber 1262985-23-8 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,6,2,9,8 and 5 respectively; the second part has 2 digits, 2 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 1262985-23:
(9*1)+(8*2)+(7*6)+(6*2)+(5*9)+(4*8)+(3*5)+(2*2)+(1*3)=178
178 % 10 = 8
So 1262985-23-8 is a valid CAS Registry Number.
1262985-23-8Relevant articles and documents
SOLID STATE FORMS OF VEMURAFENIB HYDROCHLORIDE
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, (2014/10/15)
Provided herein are solid state forms of Vemurafenib hydrochloride, processes for preparing the solid state forms, as well as pharmaceutical compositions and formulations comprising said solid state forms.
PROCESS FOR THE MANUFACTURE OF PHARMACEUTICALLY ACTIVE COMPOUNDS
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Page/Page column 9, (2011/02/25)
According to the present invention there are provided novel processes for the manufacture of the compound of formula 1 as well as novel synthesis routes for key intermediates used in those processes.
