1268259-11-5

Basic information

• Product Name: (2R,5R)-2-(2,5-di(dimethoxymethoxy)phenyl)-5-isopropyl-3,6-dimethoxy-2,5-dihydopyrazine
• CAS NO: 1268259-11-5
• Molecular Weight: 380.441
• Mol File: 1268259-11-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (2R,5R)-2-(2,5-di(dimethoxymethoxy)phenyl)-5-isopropyl-3,6-dimethoxy-2,5-dihydopyrazine(CAS DataBase Reference)
• NIST Chemistry Reference: (2R,5R)-2-(2,5-di(dimethoxymethoxy)phenyl)-5-isopropyl-3,6-dimethoxy-2,5-dihydopyrazine(1268259-11-5)
• EPA Substance Registry System: (2R,5R)-2-(2,5-di(dimethoxymethoxy)phenyl)-5-isopropyl-3,6-dimethoxy-2,5-dihydopyrazine(1268259-11-5)

Safety Data

• Hazardous Substances Data: 1268259-11-5(Hazardous Substances Data)

Upstream product

• 615-67-8 chloro-p-hydroquinone 
• 1268259-04-6 2-chloro-1,4-bis(methoxymethoxy)benzene 
• 109838-85-9 (2R)-2,5-dihydro-2-isopropyl-3,6-dimethoxypyrazine 

Relevant articles and documents

Asymmetric synthesis of α-aryl amino acids; Aryne-mediated diastereoselective arylation

An aryne-mediated α-arylation reaction of Schoellkopf's bis-lactim ether is described. Arynes were generated via an ortho-lithiation approach, affording syn-arylated products in up to 94:6 dr with moderate to good yields and excellent regioselectivities. Hydrolysis provided a variety of substituted arylglycines containing a range of functional groups without racemization.(Figure Presented)