127707-63-5

Basic information

• Product Name: beta-Hydroxyphenethyl acetate
• CAS NO: 127707-63-5
• Molecular Formula: C₁₀H₁₂O₃
• Molecular Weight: 180.203
• Mol File: 127707-63-5.mol
• Article Data: 47

Chemical Properties

• Boiling Point: 306.3°Cat760mmHg
• Flash Point: 131.4°C
• Density: 1.147g/cm³
• CAS DataBase Reference: beta-Hydroxyphenethyl acetate(CAS DataBase Reference)
• NIST Chemistry Reference: beta-Hydroxyphenethyl acetate(127707-63-5)
• EPA Substance Registry System: beta-Hydroxyphenethyl acetate(127707-63-5)

Safety Data

• Hazardous Substances Data: 127707-63-5(Hazardous Substances Data)

Upstream product

• 96-09-3 styrene oxide 
• 64-19-7 acetic acid 
• 100-42-5 styrene 
• 546-67-8 lead(IV) tetraacetate 
• 108-05-4 vinyl acetate 
• 93-56-1 phenylethane 1,2-diol 
• 7064-06-4 3-methyl-5-phenyl-4,5-dihydroisoxazole 
• 107866-54-6 1-acetyl-1H-1,2,3-triazolo<4,5-b>pyridine 
• 75178-12-0 2,2'-bipyridyl-6-yl acetate 
• 5381-93-1 1-hydroxy-1-phenyl-3-butanone 
• 6270-03-7 1,2-diacetoxy-1-phenyl-ethane 
• 108-24-7 acetic anhydride 
• 75-36-5 acetyl chloride 
• 82240-84-4 2-Chloro-4-phenyl-1,3,2-dioxastibole 

Downstream Products

• 147256-18-6 (R)-2-hydroxy-2-phenylethyl acetate 
• 147256-19-7 (S)-2-methylcarbonyloxy-1-phenylethyl acetate 
• 2243-35-8 2-acetoxyacetophenone 
• 93-56-1 phenylethane 1,2-diol 
• 6270-03-7 1,2-diacetoxy-1-phenyl-ethane 
• 98-86-2 acetophenone 
• 104-62-1 formic acid phenethyl ester 

Relevant articles and documents

Catalytic application of zinc complex of oxygen depleted 1,3-bis(pyrazole)-p-tert-butylcalix[4]arene

In this paper we have described the synthesis and coordination properties of monometallic Zinc complex of oxygen depleted bis(pyrazole)-p-tert-butylcalix[4]arene ligand. We also present the catalytic activity of the Zinc–bis(pyrazole) complex, in acetylation of alcohols and lactide polymerization.

Tandem Acid/Pd-Catalyzed Reductive Rearrangement of Glycol Derivatives

Herein, we describe the acid/Pd-tandem-catalyzed transformation of glycol derivatives into terminal formic esters. Mechanistic investigations show that the substrate undergoes rearrangement to an aldehyde under [1,2] hydrogen migration and cleavage of an oxygen-based leaving group. The leaving group is trapped as its formic ester, and the aldehyde is reduced and subsequently esterified to a formate. Whereas the rearrangement to the aldehyde is catalyzed by sulfonic acids, the reduction step requires a unique catalyst system comprising a PdII or Pd0 precursor in loadings as low as 0.75 mol % and α,α′-bis(di-tert-butylphosphino)-o-xylene as ligand. The reduction step makes use of formic acid as an easy-to-handle transfer reductant. The substrate scope of the transformation encompasses both aromatic and aliphatic substrates and a variety of leaving groups.

DBN-Catalyzed Regioselective Acylation of Carbohydrates and Diols in Ethyl Acetate

The 1,5-diazabicyclo[4.3.0]non-5-ene (DBN)-catalyzed regioselective acylation of carbohydrates and diols in ethyl acetate has been developed. The hydroxyl groups can be selectively acylated by the corresponding anhydride in EtOAc in the presence of a catalytic amount (as low as 0.1 equiv.) of DBN at room temperature to 40 °C. This method avoids metal catalysts and toxic solvents, which makes it comparatively green and mild, and it uses less organic base compared with other selective acylation methods. Mechanism studies indicated that DBN could catalyze the selective acylation of hydroxyl moieties through a dual H-bonding interaction.