128892-30-8Relevant articles and documents
Convergent synthesis of dolastatin 15 by solid phase coupling of an N- methylamino acid
Akaji, Kenichi,Hayashi, Yuzo,Kiso, Yoshiaki,Kuriyama, Naohiro
, p. 405 - 411 (1999)
Convergent synthesis of dolastatin 15 (1), a cytostatic depsipeptide isolated from the Indian Ocean sea hare, has been described. For construction of the backbone, a single-step condensation of peptide fragment 2 and pyrrolidone fragment 3 was successfull