128944-61-6

Basic information

• Product Name: 1-(benzyloxycarbonyl)-trans-3,4-dibromo-3-ethylpiperidine
• CAS NO: 128944-61-6
• Molecular Weight: 405.129
• Mol File: 128944-61-6.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 1-(benzyloxycarbonyl)-trans-3,4-dibromo-3-ethylpiperidine(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(benzyloxycarbonyl)-trans-3,4-dibromo-3-ethylpiperidine(128944-61-6)
• EPA Substance Registry System: 1-(benzyloxycarbonyl)-trans-3,4-dibromo-3-ethylpiperidine(128944-61-6)

Safety Data

• Hazardous Substances Data: 128944-61-6(Hazardous Substances Data)

Upstream product

• 536-78-7 3-ethylpyridine 
• 501-53-1 benzyl chloroformate 
• 87167-73-5 1-benzyl-3-ethyl-pyridinium chloride 
• 55077-15-1 1-benzyl-3-ethylpyridinium bromide 
• 60900-14-3 1-benzyl-3-ethyl-1,2,5,6-tetrahydropyridine 
• 128944-60-5 1-benzyloxycarbonyl-3,4-dehydro-3-ethylpiperidine 

Downstream Products

• 125213-26-5 (+/-)-2-(benzyloxycarbonyl)-6-ethyl-7-endo-chloro-2-azabicyclo<2.2.2>oct-5-ene-7-exo-carboxylic acid methyl ester 
• 125213-26-5 (+/-)-2-(benzyloxycarbonyl)-6-ethyl-7-exo-chloro-2-azabicyclo<2.2.2>oct-5-ene-7-endo-carboxylic acid methyl ester 
• 250593-27-2 2-carboxybenzyloxy-6-ethyl-2-azabicyclo[2.2.2]oct-5-ene 
• 95669-12-8 1-(benzyloxycarbonyl)-5-ethyl-1,2-dihydropyridine 

Relevant articles and documents

SYNTHESIS OF VINCA ALKALOIDS AND RELATED COMPOUNDS XLVIII SYNTHESIS OF (+)-CATHARANTHINE AND (+/-)-ALLOCATHARANTHINE

The first synthesis of natural (+)-catharanthine (1) has been achieved in a few steps and in ca. 20 percent overall yield based on indole-3-acetic acid.The isomeric (+/-)-allocatharanthine was also prepared.

Stereocontrolled total synthesis of (±)-catharanthine via radical-mediated indole formation

(matrix presented) A stereocontrolled total synthesis of (±)-catharanthine, 1, has been completed. The key step involves the radical-mediated cyclization of a highly functionalized intermediate to furnish the corresponding indole. The cyclization utilizes