129-30-6 Usage
Description
N,N'-(9,10-dioxo-1,5-anthrylene)di(acetamide) is a chemical compound synthesized from anthraquinone and acetic anhydride, resulting in the attachment of two acetamide groups to the anthraquinone structure. N,N'-(9,10-dioxo-1,5-anthrylene)di(acetamide) is known for its fluorescent properties and is utilized in various applications across different industries.
Uses
Used in Organic Synthesis:
N,N'-(9,10-dioxo-1,5-anthrylene)di(acetamide) is used as a reagent or catalyst in organic synthesis, particularly for the preparation of anthraquinone derivatives. Its unique structure and properties make it a valuable component in the synthesis of various organic compounds.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, N,N'-(9,10-dioxo-1,5-anthrylene)di(acetamide) serves as a building block for the synthesis of a range of drugs. Its versatile chemical structure allows for the development of new therapeutic agents with potential applications in medicine.
Used as a Fluorescent Dye or Tracer:
Due to its fluorescent properties, N,N'-(9,10-dioxo-1,5-anthrylene)di(acetamide) is used as a fluorescent dye or tracer in biological and chemical research. This allows researchers to track and study the behavior of molecules and compounds in various experimental settings.
Safety Precautions:
It is crucial to handle and use N,N'-(9,10-dioxo-1,5-anthrylene)di(acetamide) with caution, as it may pose health hazards. It should be used in a controlled environment with proper safety measures in place to ensure the well-being of individuals working with this compound.
Check Digit Verification of cas no
The CAS Registry Mumber 129-30-6 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 1,2 and 9 respectively; the second part has 2 digits, 3 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 129-30:
(5*1)+(4*2)+(3*9)+(2*3)+(1*0)=46
46 % 10 = 6
So 129-30-6 is a valid CAS Registry Number.
129-30-6Relevant articles and documents
Synthesis and antitumor evaluation of symmetrical 1,5-diamidoanthraquinone derivatives as compared to their disubstituted homologues
Huang, Hsu-Shan,Chiu, Hui-Fen,Tao, Chi-Wei,Chen, In-Been
, p. 458 - 464 (2007/10/03)
A series of symmetrical 1,5-diamidoanthraquinone derivatives with potentially bioreducible groups has been synthesized and their cytostatic activity against the panel of various cancer cell lines in vitro has been studied. Preliminary structure-activity relationships were established. The results indicated that compounds 5 and 18 exhibited significant potent cytotoxicity at 1.24-1.75 μM for Hepa G2 cell line; compounds 5, 16, and 18 exhibited cytotoxicity at 0.14-1.82 μM for 2.2.15 cell line as determined by XTT colorimetric assay. Two structurally related compounds, mitoxantrone and adriamycin, were tested in parallel as positive controls. In addition, it was found that compounds 5 and 18 were a more potent and specific human hepatoma cell line than mitoxantrone and showed comparable activity to adriamycin. Among them, compound 18 was the most potent for 2.2.15 cells. We have demonstrated that the anthraquinone moiety is essential for activity and that less sterically hindered substituents contribute to enhanced in vitro efficacy. Implications for amidoanthraquinone cytotoxicity as potential anticancer agents are discussed. We further delineate the nature of the pharmacophore for this class of compounds, which provides a rational basis for the structure-activity relationships.
