130115-11-6

Basic information

• Product Name: isopropyl (2R,3S,4R)-3-benzylamino-2-benzyloxy-4-hydroxybutyrate
• Synonyms: isopropyl (2R,3S,4R)-3-benzylamino-2-benzyloxy-4-hydroxybutyrate
• CAS NO: 130115-11-6
• Molecular Weight: 433.547
• Mol File: 130115-11-6.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: isopropyl (2R,3S,4R)-3-benzylamino-2-benzyloxy-4-hydroxybutyrate(CAS DataBase Reference)
• NIST Chemistry Reference: isopropyl (2R,3S,4R)-3-benzylamino-2-benzyloxy-4-hydroxybutyrate(130115-11-6)
• EPA Substance Registry System: isopropyl (2R,3S,4R)-3-benzylamino-2-benzyloxy-4-hydroxybutyrate(130115-11-6)

Safety Data

• Hazardous Substances Data: 130115-11-6(Hazardous Substances Data)

Upstream product

• 124876-74-0 Methyl (R)-(-)-α-<<(1,1-dimethylethyl)dimethylsilyl>oxy>-α-phenylacetate 
• 130115-07-0 (R)-2-(t-butyldimethylsilyloxy)-2-phenylacetaldehyde 
• 130115-17-2 Benzyl-[(R)-2-(tert-butyl-dimethyl-silanyloxy)-2-phenyl-eth-(E)-ylidene]-amine 
• 20698-91-3 (R)-methyl mandelate 
• 19810-31-2 Benzyloxyacetyl chloride 
• 130115-06-9 (R)-methyl 2-tert-butoxy-2-phenylacetate 
• 130115-08-1 (R)-2-t-butoxy-2-phenylpropanal 
• 130115-20-7 (3R,4R,4'R)-4-<<<(1,1-Dimethylethyl)dimethylsilyl>oxy>phenylmethyl>-3-phenylmethoxy-1-(phenylmethyl)azetidin-2-one 
• 67-63-0 isopropyl alcohol 
• 130115-22-9 1-Benzyl-3-benzyloxy-4-((R)-tert-butoxy-phenyl-methyl)-azetidin-2-one 
• 130115-19-4 Benzyl-[(R)-2-tert-butoxy-2-phenyl-eth-(E)-ylidene]-amine 

Downstream Products

• 119660-39-8 isopropyl (2R,3S)-3-amino-2-hydroxy-4-phenylbutyrate 
• 119642-26-1 2(R)-hydroxy-3(S)-amino-4-cyclohexylbutanoic acid 2-propyl ester 
• 141280-91-3 isopropyl (2R,3S)-3-acetamido-2-acetoxy-4-cyclohexylbutyrate 
• 121506-22-7 (2R,3S)-nor-C-statine hydrochloride 
• 130115-13-8 (4R,5R)-1-benzyl-5-<(R)-(1-benzyloxy-1-isopropoxycarbonyl)methyl>-4-phenyl-2-oxazolidone 

Relevant articles and documents

A Stereoselective Synthesis of the (2R,3S)- and (2S,3R)-3-Amino-2-hydroxybutyric Acid Derivatives, the Key Components of a Renin Inhibitor and Bestatin

The title synthesis was achieved by featuring the -cycloaddition reaction of benzyloxyketene with a chiral imine derived from methyl (R)- or (S)-mandelate, alcoholysis of the formed 3,4-cis disubstituted β-lactam under acidic conditions, and reductiv