130944-14-8

Basic information

• Product Name: 1H-Naphtho[2,1-b]pyran-2-carboxylic acid, 3-amino-1-(4-chlorophenyl)-, ethyl ester
• Synonyms: ethyl 3-amino-1-(4-chlorophenyl)-1H-benzo[f]chromene-2-carboxylate
• CAS NO: 130944-14-8
• Molecular Formula: C₂₂H₁₈ClNO₃
• Molecular Weight: 379.84
• Mol File: 130944-14-8.mol
• Article Data: 8

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1H-Naphtho[2,1-b]pyran-2-carboxylic acid, 3-amino-1-(4-chlorophenyl)-, ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Naphtho[2,1-b]pyran-2-carboxylic acid, 3-amino-1-(4-chlorophenyl)-, ethyl ester(130944-14-8)
• EPA Substance Registry System: 1H-Naphtho[2,1-b]pyran-2-carboxylic acid, 3-amino-1-(4-chlorophenyl)-, ethyl ester(130944-14-8)

Safety Data

• Hazardous Substances Data: 130944-14-8(Hazardous Substances Data)

Upstream product

• 64992-15-0 C₈H₁₅N₂O₂⁽¹⁺⁾*Cl^(1-) 
• 64-17-5 ethanol 
• 6827-40-3 diethyl 4-chlorobenzylidenemalonate 
• 135-19-3 β-naphthol 
• 2286-35-3 ethyl 3-(4-chlorophenyl)-2-cyanoacrylate 
• 104-88-1 4-chlorobenzaldehyde 
• 105-56-6 ethyl 2-cyanoacetate 

Relevant articles and documents

MCM-41@Schiff base-Co(OAc)2 as an efficient catalyst for the synthesis of pyran derivatives

Heterogeneous ordered mesoporous silica materials catalyst, MCM-41@Schiff base-Co(AcO)2, reveals high catalytic performance within the synthesis of pyran derivatives using the multicomponent reaction of aldehydes, malononitrile and 2-naphthol (

Nano polypropylenimine dendrimer (DAB-PPI-G1): As a novel nano basic-polymer catalyst for one-pot synthesis of 2-amino-2-chromene derivatives

The nano polypropylenimine dendrimer (DAB-PPI-G1) Lewis base catalyst was found to be a highly efficient and recoverable catalyst for the rapid and convenient synthesis of 2-amino-2-chromene derivatives through the three-component condensation of aromatic aldehydes, malononitrile or ethyl cyanoacetate and phenols under solvent-free conditions in excellent yields and short reaction times.

Task specific onium salt as soluble support in multicomponent synthesis of 4-aryl-2-amino-3-ethoxycarbonyl-naphthopyrans

In this paper was presented an application of task specific onium salt as soluble support in multicomponent synthesis of 2-amino-3-ethoxycarbonyl- naphthopyrans. The starting task-specific onium salt was functionalized in good yield with chloroethyl alcohol, followed by three steps containing esterification, three components reaction and cleavage from onium salt to afford naphthopyrans in 60% -88% overall yields. All of the products were characterized by IR, 1H NMR, 13C NMR and MS techniques. In this paper was presented an application of task specific onium salt as soluble support in multicomponent synthesis of 2-amino-3-ethoxycarbonyl-naphthopyrans. The starting task-specific onium salt was functionalized in good yield with chloroethyl alcohol, followed by three steps containing esterification, three components reaction and cleavage from onium salt to afford naphthopyrans in 60%-88% overall yields. All of the products were characterized by IR, 1H NMR, 13C NMR and MS techniques.