1313201-72-7

Basic information

• Product Name: C₂₁H₂₂N₈O₅
• CAS NO: 1313201-72-7
• Molecular Weight: 466.456
• Mol File: 1313201-72-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₂₁H₂₂N₈O₅(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₁H₂₂N₈O₅(1313201-72-7)
• EPA Substance Registry System: C₂₁H₂₂N₈O₅(1313201-72-7)

Safety Data

• Hazardous Substances Data: 1313201-72-7(Hazardous Substances Data)

Upstream product

• 106060-78-0 3'-azido-5'-O-benzoyl-3'-deoxythymidine 
• 1313201-66-9 C₂₁H₂₃N₅O₆ 

Downstream Products

• 1313201-83-0 C₂₁H₂₃N₉O₄ 

Relevant articles and documents

Synthesis and anti-HIV evaluation of 3′-triazolo nucleosides

A series of hitherto unknown 3′-α-[1,2,3]-substituted triazolo-2′,3′-dideoxypyrimidine nucleoside analogues of the anti-HIV 3′-azido-3′-deoxythymidine (AZT) were synthesized through catalyzed alkyne-azide 1,3-dipolar cycloaddition (Huisgen reaction). Those 3′-[1,2,3]-triazolo analogues bearing an azido alkyl chain were evaluated for their anti-HIV activity against HIV-1 in primary human lymphocytes as well as for their cytotoxicity in different cells. None of them inhibit HIV replication (EC50 > 20 μM); two of them were converted to their triphosphate form to evaluate their HIV-RT inhibition. Copyright Taylor and Francis Group, LLC.