1313483-93-0Relevant articles and documents
Nickel(ii)-catalyzed enantioselective 1,3-dipolar cycloaddition of azomethine imines with alkylidene malonates
Li, Jiangting,Lian, Xiangjin,Liu, Xiaohua,Lin, Lili,Feng, Xiaoming
, p. 5134 - 5140 (2013)
We demonstrated an asymmetric 1,3-dipolar cycloaddition of azomethine betaines with alkylidene malonates by using a chiral N,N'-dioxide- NiII complex as a catalyst. Both aromatic- and aliphatic-substituted alkylidene malonates were found to be suitable for the reaction. A range of transpyrazolone derivatives was exclusively obtained with excellent yields (up to 99% yield) and good enantioselectivities (up to 97% ee) under mild reaction conditions. The reaction could be carried out on a gram scale with the good results being maintained. Control experiments were performed to elucidate the specific diastereoselectivity of the reaction. The formation of single trans isomers was dominated by secondary orbital interactions between the ester groups of the dipolarophile and the azomethine imine. On the basis of the experimental results and previous reports, a possible catalytic model was assumed.
Photocatalytic reductive radical-radical coupling of: N, N ′-cyclicazomethine imines with difluorobromo derivatives
Xia, Peng-Ju,Ye, Zhi-Peng,Song, Dan,Ren, Ji-Wei,Wu, Han-Wen,Xiao, Jun-An,Xiang, Hao-Yue,Chen, Xiao-Qing,Yang, Hua
supporting information, p. 2712 - 2715 (2019/03/05)
A visible-light-induced difluoroalkylation of N,N′-cyclicazomethine imine was successfully realized through a novel photoredox radical-radical cross-coupling reaction. This developed protocol exhibits high functional group tolerance and affords a variety
Diastereoselective 1,3-Dipolar Cycloadditions of N,N′-Cyclic Azomethine Imines with Iminooxindoles for Access to Oxindole Spiro-N,N-bicyclic Heterocycles
Zhao, Hong-Wu,Li, Bo,Pang, Hai-Liang,Tian, Ting,Chen, Xiao-Qin,Song, Xiu-Qing,Meng, Wei,Yang, Zhao,Zhao, Yu-Di,Liu, Yue-Yang
supporting information, p. 848 - 851 (2016/03/04)
In the presence of CuI, 1,3-dipolar cycloadditions of N,N′-cyclic azomethine imines with iminooxindoles proceeded readily and furnished novel oxindole spiro-N,N-bicyclic heterocycles in moderate to excellent chemical yields with excellent diastereoselecti