131354-47-7

Basic information

• Product Name: (R)-4-Methyl-1-phenyl-pent-2-yne-1,4-diol
• Synonyms: (R)-4-Methyl-1-phenyl-pent-2-yne-1,4-diol
• CAS NO: 131354-47-7
• Molecular Weight: 190.242
• Mol File: 131354-47-7.mol
• Article Data: 8

Chemical Properties

• CAS DataBase Reference: (R)-4-Methyl-1-phenyl-pent-2-yne-1,4-diol(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-4-Methyl-1-phenyl-pent-2-yne-1,4-diol(131354-47-7)
• EPA Substance Registry System: (R)-4-Methyl-1-phenyl-pent-2-yne-1,4-diol(131354-47-7)

Safety Data

• Hazardous Substances Data: 131354-47-7(Hazardous Substances Data)

Upstream product

• 925-90-6 ethylmagnesium bromide 
• 115-19-5 2-methyl-but-3-yn-2-ol 
• 100-52-7 benzaldehyde 
• 156-60-5 trans-1,2-dichloroethylene 
• 67-64-1 acetone 
• 99067-61-5 3-chloro-1-phenyl-prop-2-yn-1-ol 
• 2028-63-9 but-3-yn-2-ol 
• 25461-80-7 4-methyl-4-hydroxy-1-phenylpent-2-yn-1-one 
• 4187-87-5 1-phenylprop-2-yn-1-ol 

Downstream Products

• 74-86-2 acetylene 
• 25461-80-7 4-methyl-4-hydroxy-1-phenylpent-2-yn-1-one 
• 56539-58-3 4-methyl-1-phenyl-pent-2-ene-1,4-diol 
• 5111-42-2 Acetic acid 4-acetoxy-4-methyl-1-phenyl-pent-2-ynyl ester 
• 5111-53-5 1-Isopropyl-2,3-diphenyl-indan 
• 63678-00-2 4,5-dihydro-2,2-dimethyl-5-phenyl-3(2H)-furanone 
• 63677-96-3 (E)-2-hydroxy-2-methyl-5-phenylpent-4-en-3-one 
• 78957-43-4 5,5-dimethyl-2-phenyl-4,5-dihydro-3(2H)-furanone 
• 88865-31-0 5-acetoxy-2-methyl-5-phenyl-3-pentyn-2-ol 
• 131354-51-3 Acetic acid (R)-4-hydroxy-4-methyl-1-phenyl-pent-2-ynyl ester 
• 493-71-0 bullatenone 
• 78957-35-4 3-acetoxy-2,2-dimethyl-5-phenyl-2,5-dihydrofuran 
• 88865-37-6 4-bromo-2,2-dimethyl-5-phenyl-4,5-dihydro-3(2H)-furanone 
• 1235384-60-7 3,4-diiodo-2,2-dimethyl-5-phenyl-2,5-dihydrofuran 

Relevant articles and documents

Direct Cross-Couplings of Propargylic Diols

[Pd(PPh3)4] catalyzes a Suzuki–Miyaura-like twofold cross-coupling sequence between underivatized propargylic diols and either aryl or alkenyl boronic acids to furnish highly substituted 1,3-dienes. Thus, 2,3-diaryl-1,3-butadienes and their dialkenic congeners ([4]dendralenes) are delivered in a (pseudo)halogen-free, single-step synthesis which supersedes existing methods. Allenols are also readily formed. Treatment of these single- and twofold cross-coupled products with acid leads to remarkably short syntheses of highly-substituted benzofulvenes and aryl indenes, respectively.

Lithiation of 1,2-dichloroethene in flow microreactors: Versatile synthesis of alkenes and alkynes by precise residence-time control

It′s all about the timing: Precise control of the residence time (tRx; see picture) of reactive intermediates in flow microreactors enables the reaction pathway of lithiated 1,2-dichloroethene to be switched to produce either alkenes or alkynes. This method also allows versatile syntheses of asymmetric disubstituted dichloroalkenes and alkynes. Copyright

Ligand accelerated indium(III)-catalyzed asymmetric alkynylation of aldehydes with 2-methyl-3-butyn-2-ol as an ethyne equivalent donor

Indium(III)-catalyzed asymmetric alkynylation of aryl, heteroaryl, alkyl and alkenyl aldehydes with 2-methyl-3-butyn-2-ol as an ethyne equivalent donor was realized, and products were obtained in moderate to good yields (up to 97%) and high enantioselecti