133464-35-4 Usage
Description
(R)-3-Benzyl 4-Methyl 2,2-Dimethyloxazolidine-3,4-Dicarboxylate, with the molecular formula C18H21NO6, is a derivative of oxazolidine, a five-membered cyclic compound containing nitrogen, oxygen, and carbon atoms. This chiral molecule features a stereogenic center at the carbon bonded to the nitrogen atom in the oxazolidine ring. Its unique structure and chirality make it a valuable intermediate in organic synthesis, particularly for the production of pharmaceuticals and agrochemicals. Additionally, (R)-3-Benzyl 4-Methyl 2,2-Dimethyloxazolidine-3,4-Dicarboxylate exhibits potential biological and pharmacological activities, which contribute to its significance in the research and development of novel drugs.
Uses
Used in Pharmaceutical Industry:
(R)-3-Benzyl 4-Methyl 2,2-Dimethyloxazolidine-3,4-Dicarboxylate is used as an intermediate in the synthesis of various pharmaceutical compounds due to its chiral nature and unique structural features. Its ability to be incorporated into complex molecular structures makes it a valuable building block for the development of new drugs with improved efficacy and selectivity.
Used in Agrochemical Industry:
In the agrochemical industry, (R)-3-Benzyl 4-Methyl 2,2-Dimethyloxazolidine-3,4-Dicarboxylate is utilized as a key intermediate in the synthesis of chiral agrochemicals. Its incorporation into these compounds can lead to enhanced target specificity, reduced environmental impact, and improved overall performance.
Used in Research and Development:
(R)-3-Benzyl 4-Methyl 2,2-Dimethyloxazolidine-3,4-Dicarboxylate is also used in the research and development of new drugs, particularly those with potential biological and pharmacological activities. Its unique structure and chirality make it an attractive candidate for exploring novel therapeutic approaches and advancing the understanding of molecular interactions in various biological systems.
Check Digit Verification of cas no
The CAS Registry Mumber 133464-35-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,3,4,6 and 4 respectively; the second part has 2 digits, 3 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 133464-35:
(8*1)+(7*3)+(6*3)+(5*4)+(4*6)+(3*4)+(2*3)+(1*5)=114
114 % 10 = 4
So 133464-35-4 is a valid CAS Registry Number.
133464-35-4Relevant articles and documents
HETEROCYCLIC COMPOUNDS FOR THE TREATMENT OF ABNORMAL CELLULAR PROLIFERATION
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Page/Page column 127-128, (2019/07/20)
This invention is in the area of heterocyclic-based compounds for the treatment of disorders involving abnormal cellular proliferation, including but not limited to tumors and cancers.
Development of a scalable chiral synthesis of MK-3281, an inhibitor of the hepatitis C virus NS5B polymerase
Colarusso, Stefania,Conte, Immacolata,Di Filippo, Marcello,Ercolani, Caterina,MacKay, Angela C.,Palumbi, Maria Cecilia,Rico Ferreira, Maria Del Rosario,Stansfield, Ian,Zaramella, Simone,Narjes, Frank,Habermann, J?rg
scheme or table, p. 1527 - 1532 (2011/08/03)
The development of a scalable chiral synthesis for the HCV NS5B inhibitor MK-3281 is being reported. Several alternative routes were explored and are being described. Georg Thieme Verlag Stuttgart ? New York.
Rearrangement of N-alkyl 1,2-amino alcohols. Synthesis of (S)-toliprolol and (S)-propanolol
Duthion, Béranger,Métro, Thomas-Xavier,Gomez Pardo, Domingo,Cossy, Janine
experimental part, p. 6696 - 6706 (2011/02/26)
N-alkyl 1,2-amino alcohols were rearranged stereospecifically by using TFAA/Et3N. This rearrangement has been used to synthesize N-isopropyl-3-(aryloxy)-2-hydroxypropylamines, β-adrenergic blocking agents such as (S)-toliprolol and (S)-propanolol.
