135304-93-7Relevant articles and documents
An efficient synthesis of substituted quinolines
Tom,Ruel
, p. 1351 - 1355 (2007/10/03)
The addition of substituted anilines to "vinamidinium" bis-tetrafluoroborate salt 1 [2-dimethylaminomethylene-1,3-bis(dimethylimmonio)propane bis-tetrafluoroborate], followed by cyclization of the resulting imino-eneamine salt and hydrolysis of the masked aldehydes 2, provide the corresponding 3-formyl quinolines 3. While the condensation of both 1 and its analogous bis-perchlorate salt and amidines are known to provide pyrimidines, we believe this is the first example of a quinoline annulation sequence with "vinamidinium" bis-tetrafluoroborate salt 1 and anilines.
REACTIVITY OF TRIFORMYLMETHANE. I. REACTIONS OF TRIFORMYLMETHANE WITH SELECTED TYPES OF AMINO COMPOUNDS
Arnold, Zdenek,Budesinsky, Milos,Pankova, Magdalena
, p. 1019 - 1031 (2007/10/02)
Reactions of triformylmethane with various types of amino compounds were investigated.Besides with ammonia, triformylmethane reacts spontaneously with primary amines, amino acids and their esters, urea and related compounds including carbamic acid derivatives.Reactions with amides of carboxylic and sulfonic acids require catalysis with Lewis acids.Primary products are aminomethylenemalonaldehyde derivatives IIIa-IIIv.Reactions of triformylmethane with excess of selected primary amines and two secondary amines (dimethylamine and morpholine) were also studied.