1373210-80-0

Basic information

• Product Name: 5-amino-1-(2,6-dichloro-4-(trifluoromethyl)phenyl)-4-(4-ethylphenyl)-1H-pyrazole-3-carbonitrile
• Synonyms: 5-amino-1-(2,6-dichloro-4-(trifluoromethyl)phenyl)-4-(4-ethylphenyl)-1H-pyrazole-3-carbonitrile
• CAS NO: 1373210-80-0
• Molecular Weight: 425.24
• Mol File: 1373210-80-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 5-amino-1-(2,6-dichloro-4-(trifluoromethyl)phenyl)-4-(4-ethylphenyl)-1H-pyrazole-3-carbonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 5-amino-1-(2,6-dichloro-4-(trifluoromethyl)phenyl)-4-(4-ethylphenyl)-1H-pyrazole-3-carbonitrile(1373210-80-0)
• EPA Substance Registry System: 5-amino-1-(2,6-dichloro-4-(trifluoromethyl)phenyl)-4-(4-ethylphenyl)-1H-pyrazole-3-carbonitrile(1373210-80-0)

Safety Data

• Hazardous Substances Data: 1373210-80-0(Hazardous Substances Data)

Upstream product

• 63139-21-9 4-ethylphenylboronic acid 
• 120068-79-3 5-amino-3-cyano-1-(2,6-dichloro-4-trifluoromethylphenyl)pyrazole 

Relevant articles and documents

Pd-catalyzed direct arylation of phenylpyrazole: Synthesis of fipronil derivatives with aryl boronic acids promoted by a stoichiometric amount of NIS

The palladium-catalyzed direct arylation of phenylpyrazole with aryl boronic acid promoted by a stoichiometric amount of NIS has been reported. Several phenyl pyrazoles, especially for those with trifluoromethyl groups, can participate in the reaction, providing a series of fipronil derivatives of 4-aryl-phenylpyrazole with potential bioactivity in moderate to good yields. All the compounds were characterized by 1H NMR, 13C NMR and HRMS spectroscopic techniques.