1380095-15-7

Basic information

• Product Name: (4R,5S)-5-benzoyl-4-(2,5-dimethoxyphenyl)oxazolidin-2-one
• Synonyms: (4R,5S)-5-benzoyl-4-(2,5-dimethoxyphenyl)oxazolidin-2-one
• CAS NO: 1380095-15-7
• Molecular Weight: 327.337
• Mol File: 1380095-15-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (4R,5S)-5-benzoyl-4-(2,5-dimethoxyphenyl)oxazolidin-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: (4R,5S)-5-benzoyl-4-(2,5-dimethoxyphenyl)oxazolidin-2-one(1380095-15-7)
• EPA Substance Registry System: (4R,5S)-5-benzoyl-4-(2,5-dimethoxyphenyl)oxazolidin-2-one(1380095-15-7)

Safety Data

• Hazardous Substances Data: 1380095-15-7(Hazardous Substances Data)

Upstream product

• 40276-11-7 (E)-1,4-dimethoxy-2-(2-nitrovinyl) benzene 
• 5633-34-1 (benzoylmethylene)dimethylsulfurane 

Relevant articles and documents

Hydrogen-bond-mediated asymmetric cascade reaction of stable sulfur ylides with nitroolefins: Scope, application and mechanism

A hydrogen-bond-mediated asymmetric [4+1] annulation/rearrangement cascade of stable sulfur ylides and nitroolefins was developed. This reaction provides a facile route to enantioenriched 4,5-substituted oxazolidinones in moderate to excellent isolated yields (65-96 %) with excellent stereocontrol (up to more than 95:5 d.r. and 97:3 e.r.). This methodology was successfully applied to the concise synthesis of two bioactive molecules. The stereocontrolled modes and mechanism have been proposed to explain the origin of this stereochemistry. Controlled cascade: A hydrogen-bond-mediated asymmetric [4+1] annulation/rearrangement cascade of stable sulfur ylides and nitroolefins was developed (see scheme). This reaction provides a facile route to enantioenriched 4,5-substituted oxazolidinones. Stereocontrolled modes and a mechanism are proposed to explain the origin of the stereochemistry. Copyright