138200-69-8Relevant articles and documents
An efficient conversion of nitroaromatics and aromatic amines to tertiary amines in one-pot way
Jung, Yeon Joo,Bae, Jong Woo,Park, Eun Soo,Chang, Yu Mi,Yoon, Cheol Min
, p. 10331 - 10338 (2003)
Reductive alkylation and reductive methylation of aromatic primary amines with carbonyls and 37% formaldehyde using decaborane in one-pot way gave the corresponding tertiary amines in high yields. The reaction condition was extended for the reduction of n
N-Dealkylation-N-nitrosation of Tertiary Aromatic Amines by n-Butyl Nitrite
Verardo, Giancarlo,Giumanini, Angelo G.,Strazzolini, Paolo
, p. 7845 - 7852 (2007/10/02)
N,N-Dialkyl aromatic amines with a variety of ring substituents are N-dealkylated and N-nitrosated efficiently by n-butyl nitrite/ammonium chloride/water at reflux temperature.Ring nitrosation was never observed, but minor amounts of m- and p-nitro amines and/or nitrosamines were formed in some cases.Ring nitration is rather a reaction of the initial substrate than a process occurring on formed nitrosamines.The leaving propensities of the initial N-substituents to yield nitrosamines were in the order benzyl >> methyl >> alkyl.Key Words: Nitrosamines; N-Dealkylation; N-Nitrosation; C-Nitration; Alkyl nitrite.