141945-70-2

Basic information

• Product Name: 4-Piperidinone, 1-[(4-nitrophenyl)methyl]-
• CAS NO: 141945-70-2
• Molecular Formula: C12H14N2O3
• Molecular Weight: 234.255
• Mol File: 141945-70-2.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 4-Piperidinone, 1-[(4-nitrophenyl)methyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Piperidinone, 1-[(4-nitrophenyl)methyl]-(141945-70-2)
• EPA Substance Registry System: 4-Piperidinone, 1-[(4-nitrophenyl)methyl]-(141945-70-2)

Safety Data

• Hazardous Substances Data: 141945-70-2(Hazardous Substances Data)

Upstream product

• 41661-47-6 piperidin-4-one 
• 100-11-8 1-bromomethyl-4-nitro-benzene 
• 41979-39-9 4-piperidone hydrochloride 
• 100-14-1 4-nitrobenzyl chloride 

Downstream Products

• 92539-18-9 4-piperidinqmine, 1-<(4-nitrophenyl)methyl>- 
• 617714-38-2 [1-(4-nitro-benzyl)-piperidin-4-ylidene]-acetic acid ethyl ester 
• 185434-58-6 [1-(4-Nitro-benzyl)-piperidin-4-yl]-acetic acid ethyl ester 
• 617714-48-4 3-methyl-1-[1-(4-nitro-benzyl)-piperidin-4-yl]-butan-2-one 
• 617714-45-1 3-methyl-1-[1-(4-nitro-benzyl)-piperidin-4-yl]-butan-2-ol 
• 617714-50-8 2-methyl-1-[1-(4-nitro-benzyl)-piperidin-4-ylmethyl]-propylamine 
• 183139-42-6 4-[1-(4-Nitro-benzyl)-piperidin-4-ylcarbamoyl]-butyric acid 

Relevant articles and documents

Design and synthesis of novel CCR3 antagonists

As part of our investigation into the development of potent CCR3 antagonists, a series of piperidine analogues was designed and prepared. Exploration of the piperidine core examined both the basicity and the location of a nitrogen, as well as conformational variants. The bicyclo-piperidine 24c was found to be the most potent inhibitor of CCR3 with an IC50 of 0.0082 μM in the binding assay and 0.0024 μM in the chemotaxis assay.

Catalytic antibody mediated hydrolysis of paraoxon

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