141956-26-5

Basic information

• Product Name: 2-phenyl-3-[2-(N,N-dimethylamino)ethyl]-1,3-thiazolidin-4-one
• CAS NO: 141956-26-5
• Molecular Weight: 250.365
• Mol File: 141956-26-5.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2-phenyl-3-[2-(N,N-dimethylamino)ethyl]-1,3-thiazolidin-4-one(CAS DataBase Reference)
• NIST Chemistry Reference: 2-phenyl-3-[2-(N,N-dimethylamino)ethyl]-1,3-thiazolidin-4-one(141956-26-5)
• EPA Substance Registry System: 2-phenyl-3-[2-(N,N-dimethylamino)ethyl]-1,3-thiazolidin-4-one(141956-26-5)

Safety Data

• Hazardous Substances Data: 141956-26-5(Hazardous Substances Data)

Upstream product

• 23956-51-6 N¹-benzylidene-N²,N²-dimethylethane-1,2-diamine 
• 2365-48-2 Methyl thioglycolate 
• 100-52-7 benzaldehyde 
• 68-11-1 mercaptoacetic acid 

Relevant articles and documents

Thiazolidin-4-one formation. Mechanistic and synthetic aspects of the reaction of imines and mercaptoacetic acid under microwave and conventional heating

Microwave irradiation of a mixture of benzylidene-anilines and mercaptoacetic acid in benzene gives 1,3-thiazolidin-4-ones in very high yield (65-90%), whereas the same reaction performed through using the conventional method, at reflux temperature, requires a much longer time and gives a much lower yield (25-69%). This difference seems to be due to some intermediates and by-products formed during the conventional reaction. On the basis of 1H NMR studies, two different mechanisms, acting in benzene and in DMF, respectively, have been hypothesized for the thiazolidin-4-one system formation.