1421747-19-4 Usage
Description
N-Hydroxylorcaserin, a metabolite of Lorcaserin (L469890, HCl), is a novel selective 5-HT2C-receptor agonist. It is primarily known for its role in the treatment of obesity, as it interacts with the serotonin 5-HT2C receptor, which is involved in the regulation of appetite and energy balance.
Uses
Used in Pharmaceutical Industry:
N-Hydroxylorcaserin is used as an active pharmaceutical ingredient for the treatment of obesity. It functions as a selective 5-HT2C-receptor agonist, helping to regulate appetite and energy balance, thus aiding in weight management and potentially improving overall health for individuals struggling with obesity.
Used in Obesity Treatment:
N-Hydroxylorcaserin is used as a therapeutic agent for obesity treatment, targeting the serotonin 5-HT2C receptor to modulate appetite and energy expenditure. This interaction can lead to a reduction in food intake and increased energy usage, contributing to weight loss and improved health outcomes for patients with obesity.
Check Digit Verification of cas no
The CAS Registry Mumber 1421747-19-4 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,4,2,1,7,4 and 7 respectively; the second part has 2 digits, 1 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 1421747-19:
(9*1)+(8*4)+(7*2)+(6*1)+(5*7)+(4*4)+(3*7)+(2*1)+(1*9)=144
144 % 10 = 4
So 1421747-19-4 is a valid CAS Registry Number.
1421747-19-4Relevant articles and documents
Late Stage Functionalization of Secondary Amines via a Cobalt-Catalyzed Electrophilic Amination of Organozinc Reagents
Gra?l, Simon,Chen, Yi-Hung,Hamze, Clémence,Tüllmann, Carl Phillip,Knochel, Paul
, p. 494 - 497 (2019)
A general preparation of polyfunctional hydroxylamine benzoates from the corresponding secondary amines is reported. This convenient synthesis allows the setup of a late-stage functionalization of various secondary amines, including pharmaceuticals and peptidic derivatives. Thus, a cross-coupling of hydroxylamine benzoates with various alkyl-, aryl-, and heteroaryl-zinc chlorides in the presence of 5 mol % CoCl2 (25 °C, 2 h) provides a range of polyfunctional tertiary amines. This method was used to prepare penfluridol and gepirone.
