1424-14-2

Basic information

• Product Name: N,N'-DIBENZYLTHIOUREA
• Synonyms: 1,3-Dibenzylthiourea;Dibenzylthiourea;sym-Dibenzylthiourea;Thiourea, bis(phenylmethyl)-;Thiourea, N,N'-bis(phenylmethyl)-;Urea, 1,3-dibenzyl-2-thio-;N,N'-DIBENZYLTHIOUREA;AKOS B029102
• CAS NO: 1424-14-2
• Molecular Formula: C₁₅H₁₆N₂S
• Molecular Weight: 256.37
• EINECS: 215-837-9
• Mol File: 1424-14-2.mol
• Article Data: 53

Chemical Properties

• Melting Point: 146-149°C
• Boiling Point: 405.4°Cat760mmHg
• Flash Point: 199°C
• Appearance: /
• Density: 1.154g/cm³
• BRN: 989212
• CAS DataBase Reference: N,N'-DIBENZYLTHIOUREA(CAS DataBase Reference)
• NIST Chemistry Reference: N,N'-DIBENZYLTHIOUREA(1424-14-2)
• EPA Substance Registry System: N,N'-DIBENZYLTHIOUREA(1424-14-2)

Safety Data

• Statements: 22
• Safety Statements: 22-36/37
• RIDADR: 2811
• TSCA: Yes
• HazardClass: 6.1
• PackingGroup: III
• Hazardous Substances Data: 1424-14-2(Hazardous Substances Data)

Usage

General Description

N,N'-Dibenzylthiourea is a chemical compound that is commonly used as a rubber accelerator and vulcanization agent in the production of rubber products. It is a white crystalline solid with the molecular formula C15H15N3S. It is typically employed in the formation of polynorbornene-based rubbers, where it acts as a sulfur donor to crosslink the polymer chains, improving the physical and mechanical properties of the final rubber product. Additionally, N,N'-Dibenzylthiourea has been found to exhibit antiviral and antibacterial properties, making it a potentially useful compound in medical and pharmaceutical applications. However, it is important to handle this chemical with care as it is toxic and can cause irritation to the skin, eyes, and respiratory system upon exposure.

Upstream product

• 75-09-2 dichloromethane 
• 100-46-9 benzylamine 
• 2382-96-9 benzo[d]oxazole-2-(3H)-thione 
• 137-26-8 Thiram 
• 97-74-5 bis(dimethylthiocarbamoyl)sulfide 
• 74734-11-5 1H-imidazole-1-carbodithioic acid methyl ester 
• 6630-99-5 1,2,3,4-thiatriazole-5-amine 
• 622-78-6 Benzyl isothiocyanate 
• 717847-92-2 N-methyl-N'-(pyrazine-2-carbonyl)-hydrazinecarbodithioic acid methyl ester 
• 78-83-1 2-methyl-propan-1-ol 
• 71-41-0 pentan-1-ol 
• 67-63-0 isopropyl alcohol 
• 71-36-3 butan-1-ol 
• 75-15-0 carbon disulfide 

Downstream Products

• 588-46-5 N-(phenylmethyl)acetamide 
• 622-78-6 Benzyl isothiocyanate 
• 76070-61-6 3-amino-4-benzyl-5-benzylimino-4,5-dihydro-1,2,4-thiadiazole 
• 110458-07-6 1,3-dibenzyl-5,5-dimethyl-4,6-dioxohexahydropyrymidine-2-thione 
• 7783-06-4 hydrogen sulfide 
• 100-46-9 benzylamine 
• 15260-36-3 1,3-dibenzyl-2-methylthiopseudourea hydroiodide 
• 3287-99-8 benzylamine hydrochloride 
• 38825-43-3 3-benzyl-2-(benzylimino)thiazolidin-4-one 
• 6721-03-5 N,N'-methanediylidenebis(1-phenylmethanamine) 
• 66907-78-6 5-benzylamino-1-benzyltetrazole 
• 107457-57-8 S-(2-amino-ethyl)-N,N'-dibenzyl-isothiourea; dihydrobromide 

Relevant articles and documents

A New Synthesis of Aliphatic Isothiocyanates from Primary Amines, Convenient for In Situ Use

Primary aliphatic amines react with carbon disulfide in the presence of BOP (benzotriazole-1-yl-oxy-tris(dimethylamino)phosphonium hexafluorophosphate) 1, giving the corresponding isothiocyanates in good to high yields and high purity; a number of isothiocyanates are synthesized and isolated or generated in situ and treated with a nucleophile.

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Gram Scalable Method to Synthesize Biscarbodiimides and Asymmetric Monocarbodiimides: A Platform to Access an Array of Phosphaguanidines, Amidines, and Guanidines

A mild, broadly functional group tolerant methodology has been developed to access a variety of mono- and bis-carbodiimides in good yield and high purity on multigram scale. Direct addition into these versatile motifs facilitated the rapid synthesis of a library of novel amidinines, guanidines, and phosphaguandines.

Direct, Microwave-Assisted Synthesis of Isothiocyanates

A microwave-assisted desulfuration of readily available dithiocarbamates, formed in situ from primary amines, leading to target isothiocyanates has been developed. This efficient protocol provides a rapid, environmentally benign route to aliphatic and aromatic isothiocyanates.