1428644-33-0Relevant articles and documents
Schiff bases of 3-[(4-amino-5-thioxo-1,2,4-triazole-3-yl) methyl]-2(3H)-benzoxazolone derivatives: Synthesis and biological activity
Urlu Cicekli, Solen,Onkol, Tijen,Ozgen, Selda,Sahin, M. Fethi
, p. 187 - 195 (2013/02/23)
New Schiff base derivatives of 3-[(4-amino-5-thioxo-1,2,4-triazole-3-yl) methyl]-2(3H)-benzoxazolone with aromatic aldehydes have been synthesized under microwave irradiation. Structures of the synthesized compounds were confirmed by IR, 1H-NMR and elemental analysis. Variable, but modest antimicrobial and antitubercular activity against the investigated strains of bacteria and fungi were observed. Among the derivatives obtained, 4-bromophenylmethylidene derivative 5j revealed significant antibacterial activity against P. aeruginosa.