143327-79-1

Basic information

• Product Name: Carbamic acid, [(1S)-1-(phenylmethyl)-2-propynyl]-, 1,1-dimethylethyl ester
• CAS NO: 143327-79-1
• Molecular Formula: C15H19NO2
• Molecular Weight: 245.321
• Mol File: 143327-79-1.mol
• Article Data: 18

Chemical Properties

• CAS DataBase Reference: Carbamic acid, [(1S)-1-(phenylmethyl)-2-propynyl]-, 1,1-dimethylethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Carbamic acid, [(1S)-1-(phenylmethyl)-2-propynyl]-, 1,1-dimethylethyl ester(143327-79-1)
• EPA Substance Registry System: Carbamic acid, [(1S)-1-(phenylmethyl)-2-propynyl]-, 1,1-dimethylethyl ester(143327-79-1)

Safety Data

• Hazardous Substances Data: 143327-79-1(Hazardous Substances Data)

Upstream product

• 72155-45-4 Boc-L-phenylalaninal 
• 27491-70-9 dimethyl diazomethylphosphonate 
• 90965-06-3 dimethyl 1-(1-diazo-2-oxopropyl)phosphonate 
• 51987-73-6 (S)-2-tert-butoxycarbonylamino-3-phenyl-propionic acid methyl ester 
• 289894-92-4 1-phenylbut-3-yn-2-yl acetate 
• 122-78-1 phenylacetaldehyde 
• 135663-97-7 1-phenylbut-3-yn-2-ol 
• 24424-99-5 di-tert-butyl dicarbonate 
• 74808-00-7 (S)-1-phenylbut-3-yn-2-amine 
• 1310480-50-2 (S)-N-(1-phenylbut-3-yn-2-yl)-2-methoxybenzenamine 
• 1133051-90-7 1-benzylprop-2-yn-1-yl pivalate 
• 176962-18-8 tert-butyl [(1S)-1-benzyl-3,3-dibromoprop-2-en-1-yl]carbamate 

Downstream Products

• 126410-30-8 (S)-1-phenylbut-3-en-2-amine 
• 756462-76-7 (R)-1-benzyl-prop-2-enylamine 
• 1198399-50-6 C₃₃H₃₇N₇O₂ 
• 1198399-52-8 C₂₉H₃₇N₇O₂ 
• 1198399-53-9 C₃₉H₄₆N₁₀O₂ 
• 1198399-49-3 C₂₃H₂₈N₄O₂ 
• 1262483-16-8 C₂₇H₃₈N₂O₄ 
• 1310480-42-2 (S)-tert-butyl 2-benzyl-2,5-dihydro-1H-pyrrole-1-carboxylate 
• 1454659-70-1 C₂₁H₃₀N₄O₄ 
• 1055964-36-7 2-{5-[⁽³⁵⁾-3-amino-4-phenylbut-1-yn-1-yl]pyridin-3-yl}-8,9-dimethoxybenzo[c][2,7]naphthyridin-4-amine 
• 1142928-73-1 C₃₈H₄₉N₉O₆Si 

Relevant articles and documents

Synthesis of 3′-triazoyl-dinucleotides as precursors of stable Phe-tRNAPhe and Leu-tRNALeu analogues

We report here the synthesis of stable Phe-tRNAPhe and Leu-tRNALeu analogues containing a 1,2,3-triazole ring instead of the ribose-amino acid ester bond. The 1,2,3-triazole ring is generated by dipolar cycloaddition of alkyne Phe and Leu analogues to 3′-azido-3′- deoxyadenosine via the CuI-catalysed Huisgen, Meldal, Sharpless 1,3-cycloaddition. The corresponding triazoyl pdCpA dinucleotides, obtained by classical phosphoramidite chemistry, were enzymatically ligated to 22-nt or 74-nt RNA generating stable Phe-tRNAPhe analogues containing the acceptor stem or full tRNA moieties, respectively. These molecules represent useful tools to study the contribution of the RNA and amino acid moieties in stabilization of aminoacyl-tRNA/protein complexes.

Triazolo-peptidomimetics: novel radiolabeled minigastrin analogs for improved tumor targeting

MG11 is a truncated analog of minigastrin, a peptide with high affinity and specificity toward the cholecystokinin-2 receptor (CCK2R), which is overexpressed by different tumors. Thus, radiolabeled MG11 derivatives have great potential for use in cancer d

As cell necrosis inhibitors of the indole compounds (by machine translation)

The invention relates to chemical formula (1) indole compounds, or its pharmaceutically acceptable salt or isomer, and in containing the same as the characteristic, as an active ingredient for the prevention or treatment of cell necrosis and its associated disease composition and method of manufacturing. (by machine translation)

Synthesis of 3′-triazoyl-dinucleotides as precursors of stable Phe-tRNAPhe and Leu-tRNALeu analogues

We report here the synthesis of stable Phe-tRNAPhe and Leu-tRNALeu analogues containing a 1,2,3-triazole ring instead of the ribose-amino acid ester bond. The 1,2,3-triazole ring is generated by dipolar cycloaddition of alkyne Phe and Leu analogues to 3′-azido-3′-deoxyadenosine via the CuI-catalysed Huisgen, Meldal, Sharpless 1,3-cycloaddition. The corresponding triazoyl pdCpA dinucleotides, obtained by classical phosphoramidite chemistry, were enzymatically ligated to 22-nt or 74-nt RNA generating stable Phe-tRNAPhe analogues containing the acceptor stem or full tRNA moieties, respectively. These molecules represent useful tools to study the contribution of the RNA and amino acid moieties in stabilization of aminoacyl-tRNA/protein complexes.