14338-21-7

Basic information

• Product Name: Aluminum, tris(4-methylphenyl)-
• CAS NO: 14338-21-7
• Molecular Formula: C21H21Al
• Molecular Weight: 300.379
• Mol File: 14338-21-7.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: Aluminum, tris(4-methylphenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Aluminum, tris(4-methylphenyl)-(14338-21-7)
• EPA Substance Registry System: Aluminum, tris(4-methylphenyl)-(14338-21-7)

Safety Data

• Hazardous Substances Data: 14338-21-7(Hazardous Substances Data)

Upstream product

• 537-64-4 bis(p-tolyl)mercury 
• 100-58-3 phenylmagnesium bromide 
• 7446-70-0 aluminum (III) chloride 
• 624-31-7 4-tolyl iodide 
• 4294-57-9 para-methylphenylmagnesium bromide 
• 106-38-7 para-bromotoluene 

Downstream Products

• 5440-76-6 (4-methylphenyl)diphenylmethanol 
• 99-94-5 p-Toluic acid 
• 1517-63-1 4-methylphenyl(phenyl)methanol 
• 6833-18-7 4-methyl-N-phenylbenzamide 
• 53040-92-9 4-(4-tolyl)anisole 
• 134-84-9 4-Methylbenzophenone 
• 1268834-05-4 4-(p-tolyl)nonan-5-one 
• 52776-14-4 2-(4-methylphenyl)cyclohexanone 
• 1443469-90-6 2,2,2-trifluoro-N-[1-(4-methylphenyl)cyclohexyl]acetamide 
• 4714-21-0 E-1-methyl-4-styryl-benzene 
• 123594-82-1 1-methoxy-3-[(4-methylphenyl)methyl]benzene 
• 16112-21-3 2-(4-methylphenyl)-1,3-benzothiazole 
• 17286-62-3 2-(4-methylphenyl)quinoxaline 
• 16107-82-7 4-(4-methylphenyl)-2-phenyl-quinazoline 

Relevant articles and documents

The inexpensive additive N-methylmorpholine effectively decreases the equivalents of nucleophiles in the catalytic highly enantioselective arylation of aryl aldehydes

Highly enantioselective arylation of aryl aldehydes catalyzed by (S)-H8-BINOL-Ti(Oi-Pr)2 complex in the presence of N-methylmorpholine (NMM) as an effective and inexpensive additive is described for the first time. We found high enan

General copper-catalyzed coupling of alkyl-, aryl-, and alkynylaluminum reagents with organohalides

We report the first example of a very general Cu-catalyzed cross-coupling of organoaluminum reagents with organohalides. The reactions proceed for the couplings of alkyl-, aryl-, and alkynylaluminum reagents with aryl and heteroaryl halides and vinyl bromides, affording the cross-coupled products in good to excellent yields. Both primary and secondary alkylaluminum reagents can be utilized as organometallic coupling partners. These reactions are not complicated by β-hydride elimination, and as a result rearranged products are not observed with secondary alkylaluminum reagents even for couplings with heteroaryl halides under "ligand-free" conditions. Radical clock experiment with a radical probe and relative reactivity study of Ph3Al with two haloarenes, 1-bromonaphthalene and 4-chlorobenzonitrile, having two different redox potentials indicates that the reaction does not involve free aryl radicals and radical anions as intermediates. These results combined with the result of the Hammett plot obtained by reacting Ph3Al with iodoarenes containing p-H, p-Me, p-F, and p-CF3 substituents, which shows a linear curve (R2 = 0.99) with a ρ value of +1.06, suggest that the current transformation follows an oxidative addition-reductive elimination pathway.

Process for the Preparation of ?-C-Aryl Glucosides

The present invention provides processes for stereoselectively preparing C-arylglucosides that can be useful as synthetic building block or drugs, including SGLT2 inhibitors.