144499-26-3

Basic information

• Product Name: 2-Quinoxalinol(9CI)
• Synonyms: 2-Quinoxalinol(9CI)
• CAS NO: 144499-26-3
• Molecular Formula: C8H6N2O
• Molecular Weight: 146.15
• Product Categories: QUINOXALINE
• Mol File: 144499-26-3.mol
• Article Data: 27

Chemical Properties

• Appearance: /
• Density: 1.347
• CAS DataBase Reference: 2-Quinoxalinol(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Quinoxalinol(9CI)(144499-26-3)
• EPA Substance Registry System: 2-Quinoxalinol(9CI)(144499-26-3)

Safety Data

• Hazardous Substances Data: 144499-26-3(Hazardous Substances Data)

Usage

Description

2-Quinoxalinol(9CI) is a heterocyclic chemical compound with the molecular formula C8H6N2O. It features a quinoxaline ring and a hydroxyl group attached to the carbon atoms, making it a versatile compound with potential applications in various fields.

Uses

Used in Pharmaceutical Industry:
2-Quinoxalinol(9CI) is used as an intermediate in the synthesis of pharmaceuticals for its potential biological activities, such as antifungal and antibacterial properties. Its unique structure allows it to be a promising candidate for the development of new drugs.
Used in Agrochemical Industry:
2-Quinoxalinol(9CI) is used as a building block in the production of agrochemicals, contributing to the development of effective pesticides and other agricultural chemicals that can protect crops and enhance yield.
Used in Organic Synthesis:
2-Quinoxalinol(9CI) is utilized as a versatile compound in organic synthesis, enabling the creation of a wide range of chemical products with various applications, from dyes to polymers.
Used in Research and Development:
2-Quinoxalinol(9CI) is employed as a subject of interest in research and development, where its properties and potential uses are continuously explored and studied to expand its applications in different industries.

Upstream product

• 16622-05-2 anhydro-1-hydroxy-3-methyl-s-triazolo<4,3-a>quinoxalinium hydroxide 
• 879-65-2 quinoxaline-2-carboxylic acid 
• 131543-46-9 Glyoxal 
• 95-54-5 1,2-diamino-benzene 
• 298-12-4 Glyoxilic acid 
• 13593-03-8 quinalphos 
• 6295-06-3 butyl glyoxalate 
• 1448-87-9 2-chloroquinoxaline 
• 922-68-9 Methyl glyoxylate 
• 67-56-1 methanol 
• 110307-62-5 C₁₁H₁₀N₆O₂ 
• 54107-98-1 3-benzenesulfonyloxyalloxazine 
• 59564-59-9 1,2,3,4-tetrahydroquinoxalin-2-one 
• 110307-56-7 1-methyl-3-benzenesulfonyloxyalloxazine 

Downstream Products

• 1385829-25-3 4-{4-[2-(4-(quinoxalin-2-yl)piperazin-1-yl)ethyl]phenyl}thiazol-2-amine 
• 1385829-26-4 N-methyl-4-{4-[2-(4-(quinoxalin-3-yl)piperazin-1-yl)ethyl]phenyl}thiazol-2-amine 
• 1385829-27-5 5-methyl-4-{4-[2-(4-(quinoxalin-2-yl)piperazin-1-yl)ethyl]phenyl}thiazol-2-amine 
• 1385829-28-6 4-{4-[2-(4-(quinoxalin-2-yl)piperazin-1-yl)ethyl]phenyl}thiazol-2-ol 
• 1385829-29-7 2-{4-[4-(2,5-dimethylthiazol-4-yl)phenethyl]piperazin-1-yl}quinoxaline 
• 1385829-30-0 N,5-dimethyl-4-{4-[2-(4-(quinoxalin-2-yl)piperazin-1-yl)ethyl]phenyl}thiazol-2-amine 
• 1385829-31-1 2-{4-[4-(2-methylthiazol-4-yl)phenethyl]piperazin-1-yl}quinoxaline 
• 55686-91-4 2-(1-piperazinyl)-quinoxaline 
• 933443-68-6 4-(quinoxalin-2-yloxy)-benzoic acid methyl ester 
• 875153-03-0 4-(quinoxalin-2-yloxy)-benzoic acid 
• 6479-18-1 1-methyl-2(1H)-quinoxalinone 

Relevant articles and documents

Decarboxylative Hydroxylation of Benzoic Acids

Herein, we report the first decarboxylative hydroxylation to synthesize phenols from benzoic acids at 35 °C via photoinduced ligand-to-metal charge transfer (LMCT)-enabled radical decarboxylative carbometalation. The aromatic decarboxylative hydroxylation is synthetically promising due to its mild conditions, broad substrate scope, and late-stage applications.

Multi-gram preparation of 7-nitroquinoxalin-2-amine

Methodologies to obtain quinoxaline compounds regioselectively are rarely reported in literature, thus regioselective and multi-gram methodologies to obtain these derivatives are desirable to explore the entire potential of these scaffolds for academic and/or commercial application. A facile and multi-gram methodology is described to obtain compound 7-nitroquinoxalin-2-amine using o-phenylenediamine, a cheap and readily available reactant, as starting material in a five-step procedure in good yields and high purity without further purification such as crystallization or column chromatography.

Combination of mTOR inhibitors and P13-kinase inhibitors, and uses thereof

The present invention provides for a method for treating a disease condition associated with PI3-kinase α and/or mTOR in a subject. In another aspect, the invention provides for a method for treating a disease condition associated with PI3-kinase α and/or mTOR in a subject. In yet another aspect, a method of inhibiting phosphorylation of both Akt (S473) and Akt (T308) in a cell is set forth.