1454691-21-4

Basic information

• Product Name: methyl 3-(acetyloxy)-3-(3-methoxyphenyl)propanoate
• Synonyms: methyl 3-(acetyloxy)-3-(3-methoxyphenyl)propanoate
• CAS NO: 1454691-21-4
• Molecular Weight: 252.267
• Mol File: 1454691-21-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: methyl 3-(acetyloxy)-3-(3-methoxyphenyl)propanoate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 3-(acetyloxy)-3-(3-methoxyphenyl)propanoate(1454691-21-4)
• EPA Substance Registry System: methyl 3-(acetyloxy)-3-(3-methoxyphenyl)propanoate(1454691-21-4)

Safety Data

• Hazardous Substances Data: 1454691-21-4(Hazardous Substances Data)

Upstream product

• 586-37-8 1-(3-Methoxyphenyl)ethanone 
• 779-81-7 methyl 3-(3-methoxyphenyl)-3-oxopropanoate 
• 72719-08-5 methyl 3-(3-methoxyphenyl)-3-hydroxypropanoate 
• 108-24-7 acetic anhydride 

Relevant articles and documents

Studies on the chemoenzymatic synthesis of (R)- and (S)-methyl 3-aryl-3-hydroxypropionates: The influence of toluene-pretreatment of lipase preparations on enantioselective transesterifications

Two series (para- and meta-substituted) of racemic methyl esters of 3-aryl-3-hydroxypropionic acid were prepared after which the enantiomers were separated by an enzyme-catalyzed transesterification. Several lipases were investigated as the catalyst. The influence of the enzyme pretreatment, as well as substrate concentration, reaction temperature, stirring manner, and substrate conversion on the stereochemical outcome of the biotransformation process were investigated in detail. The best results were achieved by using solvent-pretreated lipase from Pseudomonas fluorescens or Burkholderia cepacia suspended in toluene, and vinyl acetate as the acetyl group donor.