146606-53-3

Basic information

• Product Name: 3-Amino-thieno[2,3-b]quinoline-2-carboxylic acid (4-chloro-phenyl)-amide
• Synonyms: 3-Amino-thieno[2,3-b]quinoline-2-carboxylic acid (4-chloro-phenyl)-amide
• CAS NO: 146606-53-3
• Molecular Weight: 353.832
• Mol File: 146606-53-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-Amino-thieno[2,3-b]quinoline-2-carboxylic acid (4-chloro-phenyl)-amide(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Amino-thieno[2,3-b]quinoline-2-carboxylic acid (4-chloro-phenyl)-amide(146606-53-3)
• EPA Substance Registry System: 3-Amino-thieno[2,3-b]quinoline-2-carboxylic acid (4-chloro-phenyl)-amide(146606-53-3)

Safety Data

• Hazardous Substances Data: 146606-53-3(Hazardous Substances Data)

Upstream product

• 69513-35-5 3-Cyanoquinoline-2(1H)-thione 
• 3289-75-6 2-chloro-N-(4-chlorophenyl)acetamide 
• 146606-50-0 N-(4-Chloro-phenyl)-2-(3-cyano-quinolin-2-ylsulfanyl)-acetamide 
• 95104-21-5 2-chloroquinoline-3-carbonitrile 

Downstream Products

• 146606-62-4 2-(4-Chloro-phenyl)-3-thioxo-3,4-dihydro-2H-11-thia-2,4,10-triaza-benzo[b]fluoren-1-one 
• 539-03-7 N-(4-chlorophenyl)acetamide 
• 146606-66-8 2-methyl-4-oxo-oxazino<4',5':4,5>thieno<2,3-b>quinoline 
• 146606-69-1 2-(4-Chloro-phenyl)-3-methyl-2H-11-thia-2,4,10-triaza-benzo[b]fluoren-1-one 

Relevant articles and documents

SYNTHESIS AND REACTIONS OF SOME NEW 3-AMINO-2-SUBSTITUTED THIENOQUINOLINES

Reaction of 3-cyano-quinolin-2(1H)-thione (II) with ω-bromoacetophenones gave 3-amino-2-aroyl-thienoquinolines (IVa - IVd).Whereas, interaction of II with chloroacetanilides yielded the corresponding thioethers Va - Vc which cyclized into 3-amino-2-arylcarbamoylthienequinolines (VIa - VIc) on treatment with ethoxide.Compounds VIa - VIc were reacted with nitrous acid, triethyl orthoformate and carbon disulfide to afford the fused polycyclic compounds VIIa - VIIc, VIIIa - VIIIc, and IXa - IXc, respectively.Also, treatment of IXa - IXc with ethyl iodide gave 3-ethylthio derivatives Xa- Xc.Moreover, refluxing of VIa - VIc with acetic anhydride resulted in the formation of oxazinone XI which recyclized into pyrimidinones XIIIa - XIIIc upon reaction with aromatic amines.