14674-99-8

Basic information

• Product Name: 2-Propyn-1-one, 3-(3-methylphenyl)-1-phenyl-
• CAS NO: 14674-99-8
• Molecular Formula: C16H12O
• Molecular Weight: 220.271
• Mol File: 14674-99-8.mol
• Article Data: 37

Chemical Properties

• CAS DataBase Reference: 2-Propyn-1-one, 3-(3-methylphenyl)-1-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Propyn-1-one, 3-(3-methylphenyl)-1-phenyl-(14674-99-8)
• EPA Substance Registry System: 2-Propyn-1-one, 3-(3-methylphenyl)-1-phenyl-(14674-99-8)

Safety Data

• Hazardous Substances Data: 14674-99-8(Hazardous Substances Data)

Upstream product

• 625-95-6 3-Iodotoluene 
• 40230-90-8 (2-(3-methylphenyl)ethynyl)trimethylsilane 
• 98-88-4 benzoyl chloride 
• 766-82-5 1-ethynyl-3-methyl-benzene 
• 100-47-0 benzonitrile 
• 1864-94-4 phenyl formate 
• 591-50-4 iodobenzene 
• 201230-82-2 carbon monoxide 
• 36719-71-8 1-phenyl-3,3-tetramethylenetriazene 
• 62-53-3 aniline 
• 64-18-6 formic acid 
• 33675-43-3 1-(bromo-ethynyl)-3-methyl-benzene 
• 611-73-4 Benzoylformic acid 
• 100-52-7 benzaldehyde 

Downstream Products

• 766-82-5 1-ethynyl-3-methyl-benzene 
• 1422018-16-3 (Z)-1-phenyl-3-(m-tolyl)prop-2-yn-1-one O-methyl oxime 
• 1422018-02-7 3-phenyl-4-(phenylselenyl)-5-(m-tolyl)isoxazole 
• 1429215-43-9 phenyl 2,2-difluoro-3-(3-methylphenyl)cyclopropenyl ketone 
• 1378976-16-9 5-(3-methylphenyl)-1-phenyl-1H-1,2,3-triazole 
• 1228882-14-1 5-(3′-methylphenyl)-3-phenylisoxazole 

Relevant articles and documents

A facile and rapid route for the synthesis of Cu/Cu2O nanoparticles and their application in the Sonogashira coupling reaction of acyl chlorides with terminal alkynes

We have demonstrated a facile one-step synthetic strategy for the preparation of Cu/Cu2O nanoparticles (NPs) via a microwave method. The microwave energy acts as a driving force for the synthesis of Cu/Cu2O NPs, which makes the proce

Flexible Construction of Functionalized-Pyrroles under Palladium or Copper Catalysis in the Presence of BF3 ? Et2O

We have developed a flexible approach enabling the access to highly functionalized pyrroles under palladium or copper catalysis in the presence of BF3 ? Et2O. This catalytic methodology utilizes commercially available amines as react

Synthesis of Isoselenazoles and Isothiazoles from Demethoxylative Cycloaddition of Alkynyl Oxime Ethers

A general method for the synthesis of isoselenazoles and isothiazoles has been developed by the base-promoted demethoxylative cycloaddition of alkynyl oxime ethers using the cheap and inactive Se powder and Na2S as selenium and sulfur sources. This transformation features the direct construction of N-, Se-, and S-containing heterocycles through the formation of N-Se/S and C-Se/S bonds in one-pot reactions with excellent functional group tolerance.

Synthesis of 2-isoxazolyl-2,3-dihydrobenzofuransviapalladium-catalyzed cascade cyclization of alkenyl ethers

A novel palladium-catalyzed cascade cyclization reaction of alkenyl ethers with alkynyl oxime ethers for the construction of poly-heterocyclic scaffolds has been developed, in which the electron-rich alkene moiety functions as a three-atom unit, simultaneously dealing well with the coordination and regioselectivity of electron-rich olefins under metal catalysis. The strategy features excellent regio- and chemoselectivities as well as good functional group tolerance. Moreover, the newly formed 2-isoxazolyl-2,3-dihydrobenzofuran products can be further transformed to diverse complex heterocycles, demonstrating their potential applications in organic synthesis and medicinal chemistry.