147795-57-1Relevant articles and documents
Does the Nucleophilic Substitution of Halogen in o- and p-Halonitrobenzenes with Cyanoacetate Carbanions Proceed via Single Electron Transfer and a Nonchain Radical Process?
Makosza, Mieczyslaw,Podraza, Renata,Kwast, Andrzej
, p. 6796 - 6799 (1994)
The mechanistic pathway proposed by Zhang et al. (Zhang, X.-M.; Yang, D.-L.; Liu, Y.-C.J.Org.Chem. 1993, 58, 224) for nucleophilic substitution of halogen in o- and p-halonitrobenzenes, SET and nonchain radical process, was shown to be based on erronous e
Thiazole formation through a modified Gewald reaction
Mallia, Carl J.,Englert, Lukas,Walter, Gary C.,Baxendale, Ian R.
supporting information, p. 875 - 883 (2015/08/24)
The synthesis of thiazoles and thiophenes starting from nitriles, via a modified Gewald reaction has been studied for a number of different substrates. 1,4-Dithiane-2,5-diol was used as the aldehyde precursor to give either 2-substituted thiazoles or 2-substituted aminothiophenes depending on the substitution of the α-carbon to the cyano group.
