15093-43-3 Usage
Description
N-Phenyl-N'-(3-phenylpropyl)thiourea, a thiourea derivative with the molecular formula C16H18N2S, is a white crystalline solid that is relatively stable under normal conditions. It is primarily used as a rubber accelerator in the production of tires and other rubber products, as well as a catalyst in the synthesis of organic compounds and a stabilizer in the production of plastics. However, due to its irritant and toxic properties, it should be handled with care and proper safety precautions should be followed to avoid any potential health hazards.
Uses
Used in Rubber Industry:
N-Phenyl-N'-(3-phenylpropyl)thiourea is used as a rubber accelerator for enhancing the vulcanization process in the production of tires and other rubber products. It helps to improve the strength, elasticity, and durability of rubber products.
Used in Chemical Synthesis:
N-Phenyl-N'-(3-phenylpropyl)thiourea is used as a catalyst in the synthesis of various organic compounds. Its unique chemical properties enable it to facilitate specific reactions, leading to the formation of desired products.
Used in Plastics Industry:
N-Phenyl-N'-(3-phenylpropyl)thiourea is used as a stabilizer in the production of plastics. It helps to prevent the degradation of plastic materials, thereby improving their longevity and performance.
Check Digit Verification of cas no
The CAS Registry Mumber 15093-43-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,5,0,9 and 3 respectively; the second part has 2 digits, 4 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 15093-43:
(7*1)+(6*5)+(5*0)+(4*9)+(3*3)+(2*4)+(1*3)=93
93 % 10 = 3
So 15093-43-3 is a valid CAS Registry Number.
InChI:InChI=1/C16H18N2S/c19-16(18-15-11-5-2-6-12-15)17-13-7-10-14-8-3-1-4-9-14/h1-6,8-9,11-12H,7,10,13H2,(H2,17,18,19)
15093-43-3Relevant articles and documents
Structural requirement of phenylthiourea analogs for their inhibitory activity of melanogenesis and tyrosinase
Thanigaimalai, Pillaiyar,Lee, Ki-Cheul,Sharma, Vinay K.,Joo, Cheonik,Cho, Won-Jea,Roh, Eunmiri,Kim, Youngsoo,Jung, Sang-Hun
experimental part, p. 6824 - 6828 (2011/12/22)
Effect of a series of 1-phenylthioureas 1a-k and 1,3-disubstituted thioureas 2a-k were evaluated against melanin formation in melanoma B16 cell line and mushroom tyrosinase. Inhibitory activity of tyrosinase of 1-phenylthioureas 1a-k is parallel to their melanogenic inhibition. Thus, the melanogenic inhibition in melanoma B16 cells of 1-phenylthioureas could be the result of inhibition of tyrosinase. However, 1,3-diaryl or 1-phenyl-3- alkylthioureas, 2a-k, appears as melanogenic inhibitor without inhibition of tyrosinase. The molecular docking study of 1e and 2b to binding pocket of tyrosinase provided convincing explanation regarding the necessity of direct connection of planar phenyl to thiourea unit without N′-substitution of phenylthioureas 1 as tyrosinase inhibitor and 2 as non-tyrosinase inhibitor.