1636-25-5 Usage
Description
Ethylphenylmalonic acid, with the molecular formula C12H14O4, is an organic compound that serves as a versatile building block in the synthesis of pharmaceuticals and other organic compounds. This white crystalline solid is soluble in water and alcohol, and its carboxylic acid functional group contributes to its chemical reactivity and stability, making it a crucial intermediate in organic synthesis.
Uses
Used in Pharmaceutical Industry:
Ethylphenylmalonic acid is used as a key intermediate for the synthesis of various pharmaceuticals due to its chemical reactivity and stability. It plays a crucial role in the production of a wide range of pharmaceuticals, contributing to the development of new drugs and improving existing ones.
Used in Organic Synthesis:
Ethylphenylmalonic acid is used as a versatile intermediate in organic synthesis for the creation of various organic compounds. Its carboxylic acid functional group allows for a wide range of chemical reactions, making it an essential component in the synthesis of diverse organic molecules.
Check Digit Verification of cas no
The CAS Registry Mumber 1636-25-5 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,6,3 and 6 respectively; the second part has 2 digits, 2 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 1636-25:
(6*1)+(5*6)+(4*3)+(3*6)+(2*2)+(1*5)=75
75 % 10 = 5
So 1636-25-5 is a valid CAS Registry Number.
InChI:InChI=1/C11H12O4/c1-2-11(9(12)13,10(14)15)8-6-4-3-5-7-8/h3-7H,2H2,1H3,(H,12,13)(H,14,15)
1636-25-5Relevant articles and documents
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Verbit et al.
, p. 1649 (1975)
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Hydrolysis of 2,4-dithiophenobarbital
Tarsa, Monika,Zuchowski, Grzegorz,Stasiewicz-Urban, Anna,Bojarski, Jacek
experimental part, p. 123 - 128 (2009/06/20)
Hydrolysis of 2,4-dithiophenobarbital in aqueous solutions of pH 2 - 12 was investigated at 40 and 60°C using UV spectrophotometry. The values of reaction order, rate constants, pKal and pKa2 and activation energy were determined. The preliminary estimation of degradation products was accomplished using thin layer chromatography. The major products were isolated by circular chromatography and identified by spectroscopic and classical methods.
N-Alkyl barbiturates. A series of compounds for the study of metabolic structure-activity relationships
Treston,Hooper
, p. 1627 - 1629 (2007/10/02)
Many therapeutic agents are metabolised along multiple pathways, but up to now there have been few investigations addressing the question of which chemical features of drugs govern the participation in, and quantitative significance of, different biotransformation pathways. To assess the influence of variations of the chemical structure upon metabolim, a series of novel barbiturate analogues has been synthesized. The N1-monoalkylated and N1,N2-dialkylated phenobarbitones and 2-desoxyphenobarbitones have been synthesized via condensation of ethylphenylmalonic acid derivatives with different N-alkylated ureas or thioureas, and/or by base-catalyzed N-alkylation of different barbituric acids.