1644-22-0

Basic information

• Product Name: (pentafluoroethoxy)benzene
• Synonyms: Pentafluoroethoxybenzene
• CAS NO: 1644-22-0
• Molecular Formula: C₈H₅F₅O
• Molecular Weight: 212.1167
• Mol File: 1644-22-0.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 124.5°C at 760 mmHg
• Flash Point: 34.7°C
• Density: 1.348g/cm³
• Vapor Pressure: 15.4mmHg at 25°C
• Refractive Index: 1.402
• CAS DataBase Reference: (pentafluoroethoxy)benzene(CAS DataBase Reference)
• NIST Chemistry Reference: (pentafluoroethoxy)benzene(1644-22-0)
• EPA Substance Registry System: (pentafluoroethoxy)benzene(1644-22-0)

Safety Data

• Hazardous Substances Data: 1644-22-0(Hazardous Substances Data)

Upstream product

• 713-60-0 (1,1-dichloro-2,2,2-trifluoroethoxy)benzene 

Relevant articles and documents

Processes for preparing pentafluoroethoxy- and pentafluoroethylthiobenzene drivatives

A process for the preparation of (pentafluoroethoxy)- and (pentafluoroethylthio)benzene derivatives either from phenol, thiophenol or from halobenzene. A halobenzene is reacted with trifluoroethanol or a phenol or a thiophenol is reacted with a compound of the formula CF3 --CH2 --O--R'. The product is chlorinated and the chlorinated product is fluorinated in liquid hydrofluoric acid in the presence of a Lewis acid. The compounds obtained by the process of the present invention are used as synthesis intermediates in the phytosanitary, pharmaceutical and veterinary industries, and are used in lubricants.

Process for the preparation of compounds containing a difluoromethylene or trifluoromethyl group

A process for the preparation of compounds containing a difluoromethylene or trifluoromethyl group. A compound containing a carbonyl group, preferbly an acid, acid halide, amide, ketone or any compound containing a perhaloalkylcarbonyl moiety is placed, in anhydrous liquid hydrofluoric acid, in contact with boron trifluoride in a quantity such that the absolute pressure of boron trifluoride in the reaction system is at least one bar for a time sufficient to convert the carbonyl group to a difluormethylene or trifluoromethyl group. The compounds obtained are useful as synthesis intermediates in the pharmaceutical, plant-protection and dye industries, as anesthetics or as heat-transfer and lubricating fluids.