1656-83-3 Usage
Description
D-1-PALMITIN-2-OLEIN, also known as 2,3-diacyl-sn-glycerol with oleoyl as the 2-acyl group and palmitoyl as the 3-acyl group, is a type of glycerolipid. It is a naturally occurring compound found in various biological systems and plays a crucial role in cellular functions.
Uses
Used in Pharmaceutical Industry:
D-1-PALMITIN-2-OLEIN is used as a pharmaceutical agent for its potential therapeutic applications. It has been found to possess anti-inflammatory, anti-apoptotic, and anti-oxidative properties, making it a promising candidate for the treatment of various diseases, including neurodegenerative disorders, cardiovascular diseases, and cancer.
Used in Cosmetic Industry:
D-1-PALMITIN-2-OLEIN is used as an ingredient in cosmetic products for its moisturizing and emollient properties. It helps to maintain the skin's hydration and elasticity, providing a smooth and supple texture. It is commonly used in creams, lotions, and other skincare formulations.
Used in Food Industry:
D-1-PALMITIN-2-OLEIN is used as a food additive for its emulsifying and stabilizing properties. It helps to improve the texture, consistency, and shelf life of various food products, such as baked goods, confectionery, and dairy products.
Used in Research:
D-1-PALMITIN-2-OLEIN is used as a research tool in the study of lipid metabolism, cell signaling, and membrane biology. It aids in understanding the role of lipids in various cellular processes and their implications in health and disease.
Check Digit Verification of cas no
The CAS Registry Mumber 1656-83-3 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,6,5 and 6 respectively; the second part has 2 digits, 8 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 1656-83:
(6*1)+(5*6)+(4*5)+(3*6)+(2*8)+(1*3)=93
93 % 10 = 3
So 1656-83-3 is a valid CAS Registry Number.
1656-83-3Relevant articles and documents
Is the Mirror Image a True Reflection? Intrinsic Membrane Chirality Modulates Peptide Binding
Henriques, Sónia Troeira,Peacock, Hayden,Benfield, Aurélie H.,Wang, Conan K.,Craik, David J.
, p. 20460 - 20469 (2019)
Peptides with pharmaceutical activities are attractive drug leads, and knowledge of their mode-of-action is essential for translation into the clinic. Comparison of native and enantiomeric peptides has long been used as a powerful approach to discriminate membrane-or receptor-mediated modes-of-action on the basis of the assumption that interactions with cell membranes are independent of peptide chirality. Here, we revisit this paradigm with the cyclotide kalata B1, a drug scaffold with intrinsic membrane-binding activity whose enantiomer is less potent than native peptide. To investigate this chirality dependence, we compared peptide-lipid binding using mirror image model membranes. We synthesized phospholipids with non-natural chirality and demonstrate that native kalata B1 binds with higher affinity to phospholipids with chirality found in eukaryotic membranes. This study shows for the first time that the chiral environment of lipid bilayers can modulate the function of membrane-active peptides and challenges the view that peptide-lipid interactions are achiral.
Differential interaction of an AmB Analogue and ergosterol in enantiomeric membranes
Jeon, Ock-Youm,Carreira, Erick M.
supporting information; experimental part, p. 1772 - 1775 (2010/09/07)
An amphotericin B derivative exhibits differential interaction with vesicles formed from either natural (R)-or unnatural (S)-POPC and ergosterol. This implicates a close association between the polyene macrolide and the phospholipid bilayer and may account for its increased antifungal activity.
