16613-87-9

Basic information

• Product Name: 2-(dodecylamino)ethanol
• Synonyms: 2-(dodecylamino)ethanol;N-(2-Hydroxyethyl)-laurylamine;Einecs 240-663-5
• CAS NO: 16613-87-9
• Molecular Formula: C₁₄H₃₁NO
• Molecular Weight: 229.40204
• EINECS: 240-663-5
• Mol File: 16613-87-9.mol
• Article Data: 12

Chemical Properties

• Boiling Point: 341.2°C at 760 mmHg
• Flash Point: 58.2°C
• Appearance: /
• Density: 0.862g/cm³
• Vapor Pressure: 5.39E-06mmHg at 25°C
• Refractive Index: 1.454
• CAS DataBase Reference: 2-(dodecylamino)ethanol(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(dodecylamino)ethanol(16613-87-9)
• EPA Substance Registry System: 2-(dodecylamino)ethanol(16613-87-9)

Safety Data

• Hazardous Substances Data: 16613-87-9(Hazardous Substances Data)

Usage

Description

2-(dodecylamino)ethanol, also known as N-dodecyl-ethanolamine, is an amine-based surfactant with a molecular formula of C14H31NO. It is soluble in water and is characterized by its ability to decrease surface tension, improve wetting and spreading properties, and function as a corrosion inhibitor, emulsifier, and dispersant in various industrial applications. Additionally, it is used in personal care products for its conditioning and emulsifying properties and is considered to be relatively low in toxicity with no known adverse health effects at normal exposure levels.

Uses

Used in Industrial Applications:
2-(dodecylamino)ethanol is used as a corrosion inhibitor, emulsifier, and dispersant for its ability to decrease surface tension and improve wetting and spreading properties.
Used in Personal Care Products:
In the personal care industry, 2-(dodecylamino)ethanol is used as a conditioning and emulsifying agent in products such as shampoos and conditioners.

InChI:InChI=1/C14H31NO/c1-2-3-4-5-6-7-8-9-10-11-12-15-13-14-16/h15-16H,2-14H2,1H3

Upstream product

• 124-22-1 n-Dodecylamine 
• 107-07-3 2-chloro-ethanol 
• 75-21-8 oxirane 
• 143-15-7 1-dodecylbromide 
• 51323-71-8 dodecyl mesylate 
• 141-43-5 ethanolamine 
• 112-52-7 1-chlorododecane 
• 4292-19-7 1-Iodododecane 
• 4763-40-0 N-(2-cyanoethyl)dodecylamine 

Downstream Products

• 74263-50-6 3-[dodecyl-(2-hydroxy-ethyl)-amino]-propane-1,2-diol 
• 30954-08-6 4-(2-Dodecylamino-ethylamino)-benzenesulfonic acid 
• 124-22-1 n-Dodecylamine 
• 1541-67-9 N-lauryldiethanolamine 

Relevant articles and documents

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COMPOUNDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF AGENTS

The disclosure features amino lipids and compositions involving the same. Nanoparticle compositions include an amino lipid as well as additional lipids such as phospholipids, structural lipids, PEG lipids, or a combination thereof. Nanoparticle compositions further including therapeutic and/or prophylactic agents such as RNA are useful in the delivery of therapeutic and/or prophylactic agents to mammalian cells or organs to, for example, regulate polypeptide, protein, or gene expression.

Lipophilic gold(I) complexes with 1,3,4-oxadiazol-2-thione or 1,3-thiazolidine-2-thione moieties: synthesis and their cytotoxic and antimicrobial activities

Novel lipophilic gold(I) complexes containing 1,3,4-oxadiazol-2-thione or 1,3-thiazolidine-2-thione derivatives were synthesized and characterized by IR, high resolution mass spectrometry, and 1H, 13C 31P NMR. The cytotoxicity of the compounds was evaluated considering cisplatin and/or auranofin as reference in different tumor cell lines: colon cancer (CT26WT), metastatic skin melanoma (B16F10), breast adenocarcinoma (MCF-7), cervical carcinoma (HeLa), glioblastoma (M059?J). Normal human lung fibroblasts (GM07492-A) and kidney normal cell (BHK-21) were also evaluated. The gold(I) complexes were more active than their respective free ligands and cisplatin. Furthermore, antibacterial activity was evaluated against Gram-positive bacteria Staphylococcus aureus ATCC 25213, Staphylococcus epidermidis ATCC 12228 and Gram-negative bacteria Escherichia coli ATCC 11229 and Pseudomonas aeruginosa ATCC 27853 and expressed as the minimum inhibitory concentration (MIC). The complexes exhibited lower MIC values when compared to the ligands and chloramphenicol against Gram-positive bacteria and Gram-negative bacteria. Escherichia coli was sensitive one to the action of gold(I) complexes.