166322-67-4Relevant articles and documents
Studies toward the synthesis of caramboxin analogues
Oliveira Filho, Ronaldo E.,Higa, Vanessa M.,Omori, álvaro T.
, p. 528 - 540 (2019/08/26)
Intrigued by the recent discovery of caramboxin by Brazilian researchers, we present the results from our studies toward the racemic synthesis of caramboxin analogs through the ortho-carboxylation of 3,5-dimethoxy benzyl derivatives. Three different approaches were tested, and the route involving a Vilsmeier-Haack formylation followed by a Lindgren oxidation provide a potential intermediate for the synthesis of several caramboxin analogs.
Synthesis studies toward chloroazaphilone and vinylogous γ-pyridones: Two common natural product core structures
Wei, Wan-Guo,Yao, Zhu-Jun
, p. 4585 - 4590 (2007/10/03)
Chloroazaphilone is a common structure found in a number of natural products. Reported herein is a practical synthesis of a model chloroazaphilone that utilizes Pb(OAc)4 oxidation of HClO4/ HOAc pyrinium salt in a key one-pot operati
Concise asymmetric syntheses of radicicol and monocillin I
Garbaccio,Stachel,Baeschlin,Danishefsky
, p. 10903 - 10908 (2007/10/03)
Radicicol (1) exhibits potent anticancer properties in vitro, which are likely to be mediated through its high affinity (20 nM) for the molecular chaperone Hsp90. Recently, we reported the results of a synthetic program targeting radicicol (1) and monocil
