1701-73-1

Basic information

• Product Name: 1-(4-Pyridinyl)pentane-1-one
• Synonyms: 1-(4-Pyridinyl)-1-pentanone;1-(4-Pyridinyl)pentane-1-one;4-Valerylpyridine;1-(PYRIDIN-4-YL)PENTAN-1-ONE
• CAS NO: 1701-73-1
• Molecular Formula: C₁₀H₁₃NO
• Molecular Weight: 163.24
• Mol File: 1701-73-1.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 290.31°C (rough estimate)
• Flash Point: 120.4°C
• Appearance: /
• Density: 1.0508 (rough estimate)
• Vapor Pressure: 0.00998mmHg at 25°C
• Refractive Index: 1.5400 (estimate)
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 1-(4-Pyridinyl)pentane-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(4-Pyridinyl)pentane-1-one(1701-73-1)
• EPA Substance Registry System: 1-(4-Pyridinyl)pentane-1-one(1701-73-1)

Safety Data

• Hazardous Substances Data: 1701-73-1(Hazardous Substances Data)

Usage

Safety Profile

A poison by intraperitoneal route. A flammable liquid. When heated to decomposition it emits toxic vapors of NOx.

InChI:InChI=1/C10H13NO/c1-2-3-4-10(12)9-5-7-11-8-6-9/h5-8H,2-4H2,1H3

Upstream product

• 6843-37-4 N-methylisonicotinamide 
• 109-72-8 n-butyllithium 
• 106-94-5 propyl bromide 
• 872-85-5 pyridine-4-carbaldehyde 
• 23389-77-7 1-(pyridin-4-yl)pentan-1-ol 
• 100-48-1 pyridine-4-carbonitrile 
• 693-03-8 n-butyl magnesium bromide 
• 39178-35-3 isonicotinoyl chloride hydrochloride 

Downstream Products

• 1802-20-6 3-pentyl-pyridine 

Relevant articles and documents

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The anion of 3-methyl-2-pyridin-4-yl-1,3-oxazine

n-Butyllithium at -78°C readily abstracts the methine proton from the title compound. The anion reacts efficiently with a range of electrophiles to provide 4-pyridyl ketones upon acid hydrolysis.

Ligand interaction of sustituted pyridines with cytochrome P-450.

A series of pyridyl ketones and alkyl pyridines was evaluated as type II ligands for cytochrome P-450. Activity as type II ligands was evaluated in terms of the lipid solubility and the pKa values of the compounds.