1706-60-1

Basic information

• Product Name: Acetic acid, (4-mercaptophenoxy)-, methyl ester
• CAS NO: 1706-60-1
• Molecular Formula: C9H10O3S
• Molecular Weight: 198.243
• Mol File: 1706-60-1.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: Acetic acid, (4-mercaptophenoxy)-, methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Acetic acid, (4-mercaptophenoxy)-, methyl ester(1706-60-1)
• EPA Substance Registry System: Acetic acid, (4-mercaptophenoxy)-, methyl ester(1706-60-1)

Safety Data

• Hazardous Substances Data: 1706-60-1(Hazardous Substances Data)

Upstream product

• 317319-08-7 (4-dimethylcarbamoylsulfanyl-phenoxy)-acetic acid methyl ester 
• 167012-47-7 methyl [4-(4-[methoxycarbonylmethoxy]phenyldithio)phenoxy]acetate 
• 15015-57-3 bis(4-hydroxyphenyl)disulfide 
• 637-89-8 4-sulfanylphenol 
• 70067-75-3 methyl 2-(4-hydroxyphenoxy)acetate 
• 583883-83-4 (4-dimethylthiocarbamoyloxy-phenoxy)-acetic acid methyl ester 
• 56077-62-4 (4-thiocyanato-phenoxy)-acetic acid methyl ester 

Downstream Products

• 53040-04-3 2-(4-methoxycarbonylmethoxy-phenylsulfanyl)-4-methyl-thiazole-5-carboxylic acid ethyl ester 
• 317318-45-9 {4-[4-methyl-2-(4-trifluoromethyl-phenyl)-oxazol-5-ylmethylsulfanyl]-phenoxy}-acetic acid methyl ester 
• 918164-62-2 methyl (4-[3-methyl-5-(4-trifluoromethylphenyl)thien-2-ylmethylthio]phenoxy)acetate 
• 918164-61-1 methyl (4-[4-methyl-5-(4-trifluoromethylphenyl)thien-2-ylmethylthio]phenoxy)acetate 
• 58535-96-9 2-(4-methoxycarbonylmethoxy-phenylsulfanyl)-4-methyl-thiazole-5-carboxylic acid 
• 58536-09-7 [4-(4-methyl-thiazole-2-sulfonyl)-phenoxy]-acetic acid methyl ester 
• 58536-08-6 [4-(4-methyl-thiazol-2-ylsulfanyl)-phenoxy]-acetic acid methyl ester 
• 58536-07-5 [4-(4-methyl-thiazol-2-ylsulfanyl)-phenoxy]-acetic acid 
• 53040-05-4 2-(4-carboxymethoxy-phenylsulfanyl)-4-methyl-thiazole-5-carboxylic acid ethyl ester 
• 58536-02-0 2-(4-carboxymethoxy-phenylsulfanyl)-4-methyl-thiazole-5-carboxylic acid 
• 317318-65-3 methyl 2-{4-[({4-methyl-2-[4-(trifluoromethyl)phenyl]-1,3-thiazol-5-yl}methyl)sulfanyl]phenoxy}acetate 
• 873066-39-8 {4-[4-phenyl-2-(4-trifluoromethyl-phenyl)-thiazol-5-ylmethylsulfanyl]-phenoxy}-acetic acid methyl ester 
• 873066-38-7 {4-[4-furan-2-yl-2-(4-trifluoromethyl-phenyl)-thiazol-5-ylmethylsulfanyl]-phenoxy}-acetic acid methyl ester 

Relevant articles and documents

Synthesis of the PPARβ/δ-selective agonist GW501516 and C4-thiazole-substituted analogs

Sequential, position-selective, Pd-catalyzed cross-coupling reactions of 2,4-dibromo-5-hydroxymethylthiazole provided the scaffold for the synthesis of GW501516, the most potent PPARβ/δ agonist yet described, and equally selective analogs at the thiazole-

Compounds that modulate PPAR activity and methods of preparation

This invention relates to compounds that alter PPAR activity. The invention also relates to pharmaceutically acceptable salts of the compounds, pharmaceutically acceptable compositions comprising the compounds or their salts, and methods of using them as therapeutic agents for treating or preventing dyslipidemia, hypercholesterolemia, obesity, hyperglycemia, atherosclerosis, hypertriglyceridemia and hyperinsulinemia in a mammal. The present invention also relates to methods for making the disclosed compounds.

Compounds that modulate PPAR activity and methods for their preparation

This invention discloses compounds that alter PPAR activity. The invention also discloses pharmaceutically acceptable salts of the compounds, pharmaceutically acceptable compositions comprising the compounds or their salts, and methods of using them as therapeutic agents for treating or preventing disipidemia, hypercholesteremia, obesity, eating disorders, hyperglycemia, atherosclerosis, hypertriglyceridemia, hyperinsulinemia and diabetes in a mammal as well as methods of supressing appetite and modulating leptin levels in a mammal. The present invention also discloses methods for making the disclosed compounds.