17244-78-9

Basic information

• Product Name: (1S,2R)-1,2-diphenyl-2-piperidin-1-ylethanol
• CAS NO: 17244-78-9
• Molecular Weight: 281.398
• Mol File: 17244-78-9.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: (1S,2R)-1,2-diphenyl-2-piperidin-1-ylethanol(CAS DataBase Reference)
• NIST Chemistry Reference: (1S,2R)-1,2-diphenyl-2-piperidin-1-ylethanol(17244-78-9)
• EPA Substance Registry System: (1S,2R)-1,2-diphenyl-2-piperidin-1-ylethanol(17244-78-9)

Safety Data

• Hazardous Substances Data: 17244-78-9(Hazardous Substances Data)

Upstream product

• 110-89-4 piperidine 
• 1689-71-0 cis-1,2-diphenyloxirane 
• 1439-07-2 trans-Stilbene oxide 
• 6281-83-0 α-piperidino-deoxybenzoin; hydrochloride 
• 111-24-0 1,5-dibromo-pentane 
• 23364-44-5 (1S,2R)-2-Amino-1,2-diphenylethanol 
• 1484-50-0 desyl bromide 
• 447-31-4 Desyl chloride 
• 119-53-9 2-hydroxy-2-phenylacetophenone 
• 794-05-8 1,2-diphenyl-2-(1-piperidinyl)ethanone 

Downstream Products

• 17243-73-1 ((RS,SR)-α'-hydroxy-bibenzyl-α-yl)-1-methyl-piperidinium; iodide 

Relevant articles and documents

Photochemistry of Intramolecular Charge Transfer Excited States in Donor-Acceptor-Substituted Diamines

The photochemistry and photophysics of 1,2-diamines C5H10NCHPhCHPhNHC6H4R (1, R=CN, and 2, R=4-pyridyl) have been examined.These compounds display a strong absorption band in the near-UV which is due to intramolecular charge transfer from the secondary amine group to the 4-cyanophenyl or (4-pyridyl)phenyl acceptor unit.Photoexcitation into this absorption band leads to moderately intense fluorescence from the 1LE state of the charge transfer chromophore and to homolytic bond fragmentation across the 1,2 C-C bond with moderate quantum efficiency.Detailed photochemical and photophysical studies reveal that the bond fragmentation reaction ensues from a second intramolecular charge transfer excited state (denoted 1CT) which is based on electron transfer from the tertiary piperidine nitrogen to the 4-cyanophenyl or (4-pyridyl)phenyl unit.Photochemical product analysis reveals that erythro -> threo (or threo -> erythro) isomerization occurs under both argon-degassed and air-saturated conditions.This observation indicates that recombination of the radicals formed by bond fragmentation occurs, both within the geminate pair and between free radicals that have escaped the solvent cage.Analysis of fluorescence, transient absorption, and steady-state photochemical kinetics data indicates that (1) internal conversion from the 1LE state to the 1CT state by intramolecular electron transfer occurs with k>/=109 s-1 in all of the diamines; (2) bond fragmentation within the 1CT state occurs with k>/=108 s-1 in each of the diamines; (3) bond fragmentation may be faster in erythro-1 than in threo-1.

Highly enantioselective Henry reactions of aromatic aldehydes catalyzed by an amino alcohol-copper(II) complex

Amino alcohol-CuII catalyst: Highly enantioselective Henry reactions between aromatic aldehydes and nitromethane have been developed. The reactions were catalyzed by an easily available and operationally simple amino alcohol-copper(II) catalyst