172485-84-6

Basic information

• Product Name: Cbz-D-Met-NH₂
• Synonyms: Cbz-D-Met-NH₂
• CAS NO: 172485-84-6
• Molecular Weight: 282.364
• Mol File: 172485-84-6.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Cbz-D-Met-NH₂(CAS DataBase Reference)
• NIST Chemistry Reference: Cbz-D-Met-NH₂(172485-84-6)
• EPA Substance Registry System: Cbz-D-Met-NH₂(172485-84-6)

Safety Data

• Hazardous Substances Data: 172485-84-6(Hazardous Substances Data)

Upstream product

• 1152-62-1 (2R)-2-[[(benzyloxy)carbonyl]amino]-4-(methylsulfanyl)butanoic acid 

Relevant articles and documents

Amidation of carboxylic acids via the mixed carbonic carboxylic anhydrides and its application to synthesis of antidepressant (1S,2R)-tranylcypromine

Primary amidations of carboxylic acids 1 or 3 with NH4Cl in the presence of ClCO2Et and Et3N were developed to afford the corresponding primary amides in 22% to quantitative yields. Additionally, we have applied the amidation to the preparation of various amides containing hydroxamic acids and achieved the synthesis of (1S,2R)-tranylcypromine as an antidepressant medicine via Lossen rearrangement.