174684-58-3 Usage
Description
(S)-1-benzyl-3-(tert-butyldimethylsilyloxy)pyrrolidine-2,5-dione is a versatile chemical compound that belongs to the class of pyrrolidine-2,5-diones. It is characterized by the presence of a benzyl group, a tert-butyldimethylsilyloxy group, and a pyrrolidine-2,5-dione moiety. (S)-1-benzyl-3-(tert-butyldimethylsilyloxy)pyrrolidine-2,5-dione is known for its ability to undergo various chemical transformations, such as nucleophilic substitution, deprotection of silyl ethers, and asymmetric synthesis. Its stereochemistry also enables the creation of enantioselective products, making it a valuable tool in the production of chiral compounds. Overall, (S)-1-benzyl-3-(tert-butyldimethylsilyloxy)pyrrolidine-2,5-dione is a promising building block in organic synthesis and pharmaceutical research.
Uses
Used in Organic Synthesis:
(S)-1-benzyl-3-(tert-butyldimethylsilyloxy)pyrrolidine-2,5-dione is used as a building block for the synthesis of various organic compounds. Its unique structure and functional groups allow for a wide range of chemical transformations, making it a valuable asset in the development of new molecules with specific properties and applications.
Used in Pharmaceutical Research:
In the pharmaceutical industry, (S)-1-benzyl-3-(tert-butyldimethylsilyloxy)pyrrolidine-2,5-dione is used as a key intermediate in the development of new drugs. Its ability to create enantioselective products is particularly important in drug discovery, as the stereochemistry of a compound can significantly impact its biological activity and safety profile.
Used in Chiral Compound Production:
(S)-1-benzyl-3-(tert-butyldimethylsilyloxy)pyrrolidine-2,5-dione is used as a starting material for the production of chiral compounds. (S)-1-benzyl-3-(tert-butyldimethylsilyloxy)pyrrolidine-2,5-dione's stereochemistry plays a crucial role in determining the properties and applications of the resulting chiral products, making it an essential tool in the field of asymmetric synthesis.
Check Digit Verification of cas no
The CAS Registry Mumber 174684-58-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,7,4,6,8 and 4 respectively; the second part has 2 digits, 5 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 174684-58:
(8*1)+(7*7)+(6*4)+(5*6)+(4*8)+(3*4)+(2*5)+(1*8)=173
173 % 10 = 3
So 174684-58-3 is a valid CAS Registry Number.
174684-58-3Relevant articles and documents
COMPOUNDS INHIBITING LEUCINE-RICH REPEAT KINASE ENZYME ACTIVITY
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, (2014/09/29)
Provided are indazole compounds which are potent inhibitors of LRRK2 kinase and useful in the treatment or prevention of diseases in which LRRK2 kinase is involved. Also provided are pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which LRRK2 kinase is involved.
COMPOUNDS INHIBITING LEUCINE-RICH REPEAT KINASE ENZYME ACTIVITY
-
, (2014/09/29)
The present invention is directed to indazole compounds which are potent inhibitors of LRRK2 kinase and useful in the treatment or prevention of diseases in which the LRRK2 kinase is involved, such as Parkinson's Disease. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which LRRK-2 kinase is involved.
A flexible non-amino acid-based formal asymmetric synthesis of naturally occurring (2R,3S)-2-aminotetradeca-5,7-dien-3-ol: Observation of a remarkable protecting group effect
He, Bi-Yan,Wu, Tian-Jun,Yu, Xian-Yong,Huang, Pei-Qiang
, p. 2101 - 2108 (2007/10/03)
A flexible non-amino acid-based formal asymmetric synthesis of naturally occurring antimicrobial (2R,3S)-2-aminotetradeca-5,7-dien-3-ol is reported. The method features a flexible and highly regioselective Grignard addition to (S)-malimide followed by a t
